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Nagpal SJ, Mukhija D, Patel P. Fusobacterium nucleatum: a rare cause of pyogenic liver abscess. Springerplus. 2015;4:283doi: 10.1186/s40064-015-1090-8.
Nagpal, S. J., Mukhija, D., & Patel, P. (2015). Fusobacterium nucleatum: a rare cause of pyogenic liver abscess. SpringerPlus, 4283. https://doi.org/10.1186/s40064-015-1090-8
Nagpal, Sajan Jiv Singh, et al. "Fusobacterium nucleatum: a rare cause of pyogenic liver abscess." SpringerPlus vol. 4 (2015): 283. doi: https://doi.org/10.1186/s40064-015-1090-8
Nagpal SJ, Mukhija D, Patel P. Fusobacterium nucleatum: a rare cause of pyogenic liver abscess. Springerplus. 2015 Jun 19;4:283. doi: 10.1186/s40064-015-1090-8. eCollection 2015. PMID: 26101735; PMCID: PMC4472653.
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Springerplus. 2015 Jun 19;4:283. doi: 10.1186/s40064-015-1090-8. eCollection 2015.

Fusobacterium nucleatum: a rare cause of pyogenic liver abscess.

SpringerPlus

Sajan Jiv Singh Nagpal, Dhruvika Mukhija, Preethi Patel

Affiliations

  1. Department of Internal Medicine, Cleveland Clinic, Cleveland, OH 44195 USA.
  2. Department of Hospital Medicine, Cleveland Clinic, Cleveland, OH 44195 USA.

PMID: 26101735 PMCID: PMC4472653 DOI: 10.1186/s40064-015-1090-8

Abstract

While pyogenic liver abscesses are uncommon, they are associated with significant mortality and morbidity. Most pyogenic liver abscesses are polymicrobial and are caused by enteric bacteria and anaerobes. Rarely, mono-microbial infections may occur, typically in immunocompromised individuals. We report the unusual case of a 69 year-old immunocompetent female who developed a pyogenic liver abscess due to Fusobacterium nucleatum infection, likely from a dental source. Poor oropharyngeal hygiene seems to have a major role in infection from this organism and therefore F. nucleatum should be considered as a differential for causes of pyogenic liver abscess in such patients. Drainage of the abscess and antibiotic therapy are the mainstays of therapy.

Keywords: Fusobacterium; Immunocompromised state; Poor dental hygiene; Pyogenic liver abscess

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