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Kim I, Min KH, Yeo M, et al. Unusual Case of Cerebral Venous Thrombosis in Patient with Crohn's Disease. Case Rep Neurol. 2015;7(2):115-20doi: 10.1159/000430805.
Kim, I., Min, K. H., Yeo, M., Kim, J. S., Lee, S. H., Lee, S. S., Shin, K. S., Youn, S. J., & Shin, D. I. (2015). Unusual Case of Cerebral Venous Thrombosis in Patient with Crohn's Disease. Case reports in neurology, 7(2), 115-20. https://doi.org/10.1159/000430805
Kim, Inha, et al. "Unusual Case of Cerebral Venous Thrombosis in Patient with Crohn's Disease." Case reports in neurology vol. 7,2 (2015): 115-20. doi: https://doi.org/10.1159/000430805
Kim I, Min KH, Yeo M, Kim JS, Lee SH, Lee SS, Shin KS, Youn SJ, Shin DI. Unusual Case of Cerebral Venous Thrombosis in Patient with Crohn's Disease. Case Rep Neurol. 2015 May 13;7(2):115-20. doi: 10.1159/000430805. eCollection 2015. PMID: 26078745; PMCID: PMC4463793.
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Case Rep Neurol. 2015 May 13;7(2):115-20. doi: 10.1159/000430805. eCollection 2015.

Unusual Case of Cerebral Venous Thrombosis in Patient with Crohn's Disease.

Case reports in neurology

Inha Kim, Kyung-Hyun Min, Minju Yeo, Ji Seon Kim, Sung Hyun Lee, Sang Soo Lee, Kyeong Seob Shin, Sei Jin Youn, Dong Ick Shin

Affiliations

  1. Neurology, Chungbuk National University Hospital, Cheongju, Korea.
  2. Department of Neurology, Chungbuk National University Hospital, Chungbuk National University College of Medicine, Cheongju, Korea.
  3. Department of Laboratory Medicine, Chungbuk National University Hospital, Chungbuk National University College of Medicine, Cheongju, Korea.
  4. Department of Internal Medicine, Chungbuk National University Hospital, Chungbuk National University College of Medicine, Cheongju, Korea.

PMID: 26078745 PMCID: PMC4463793 DOI: 10.1159/000430805

Abstract

The development of cerebral venous thrombosis (CVT) as a secondary complication of Crohn's disease (CD) seems to be rare, but it is generally accepted that the disease activity of CD contributes to the establishment of a hypercoagulable state. Here, we describe a case of CVT that developed outside the active phase of CD. A 17-year-old male visited the emergency room because of a sudden onset of right-sided weakness and right-sided hypesthesia. He had been diagnosed with CD 1 year before and was on a maintenance regimen of mesalazine and azathioprine. He did not exhibit any symptoms indicating a CD flare-up (bloody stools, abdominal pain, complications, or weight loss). A brain MRI scan revealed an acute infarction of the left frontal cortex and a cortical subarachnoid hemorrhage. Additionally, a magnetic resonance venography revealed a segmental filling defect in the superior sagittal sinus and also the non-visualizability of some bilateral cortical veins. The characteristics of the present case suggest that the risk of CVT is most likely related to CD per se rather than disease activity associated with CD.

Keywords: Cerebral venous thrombosis; Crohn's disease; Disease activity

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