Display options
Cite
Astudillo R, Suy A, Alijotas-Reig J, et al. Expectant management in pregnant women with early and severe preeclampsia and concomitant risk factors. Pregnancy Hypertens. 2013;3(4):235-41doi: 10.1016/j.preghy.2013.06.004.
Astudillo, R., Suy, A., Alijotas-Reig, J., Carreras, E., Llurba, E., Goya, M., Higueras, T., & Cabero, L. (2013). Expectant management in pregnant women with early and severe preeclampsia and concomitant risk factors. Pregnancy hypertension, 3(4), 235-41. https://doi.org/10.1016/j.preghy.2013.06.004
Astudillo, R, et al. "Expectant management in pregnant women with early and severe preeclampsia and concomitant risk factors." Pregnancy hypertension vol. 3,4 (2013): 235-41. doi: https://doi.org/10.1016/j.preghy.2013.06.004
Astudillo R, Suy A, Alijotas-Reig J, Carreras E, Llurba E, Goya M, Higueras T, Cabero L. Expectant management in pregnant women with early and severe preeclampsia and concomitant risk factors. Pregnancy Hypertens. 2013 Oct;3(4):235-41. doi: 10.1016/j.preghy.2013.06.004. Epub 2013 Jul 16. PMID: 26103802.
Copy Download .nbib Format: NLM
Share it on

Pregnancy Hypertens. 2013 Oct;3(4):235-41. doi: 10.1016/j.preghy.2013.06.004. Epub 2013 Jul 16.

Expectant management in pregnant women with early and severe preeclampsia and concomitant risk factors.

Pregnancy hypertension

R Astudillo, A Suy, J Alijotas-Reig, E Carreras, E Llurba, M Goya, T Higueras, L Cabero

Affiliations

  1. High Risk Obstetric Unit, Vall d'Hebron University Hospital, Universitat Autònoma de Barcelona, Barcelona, Spain.
  2. High Risk Obstetric Unit, Vall d'Hebron University Hospital, Universitat Autònoma de Barcelona, Barcelona, Spain. Electronic address: [email protected].
  3. Systemic Autoimmune Disease Unit, Department of Medicine I, Vall d'Hebron University Hospital, Barcelona, Spain; Universitat Autònoma de Barcelona, Barcelona, Spain.
  4. Maternal Fetal Medicine Unit, Vall d'Hebron University Hospital, Barcelona, Spain; Universitat Autònoma de Barcelona, Barcelona, Spain.
  5. Obstetric Department, Vall d'Hebron University Hospital, Barcelona, Spain; Universitat Autònoma de Barcelona, Barcelona, Spain.

PMID: 26103802 DOI: 10.1016/j.preghy.2013.06.004

Abstract

AIM: The aim of this study was to demonstrate that women with severe early-onset preeclampsia and concomitant risk factors benefit from expectant management.

METHODS: This retrospective study was conducted between January 2009 and December 2010. Stable women with severe preeclampsia between 23+6 and 33+6weeks of gestation were admitted to the IOCU for conservative management. They were classified into two groups: those with concomitant risk factors, i.e. associated medical conditions, HELLP syndrome, severe oligohydramnios, fetal growth restriction and multiple pregnancies (group A) and those without (group B). P values lesser than 0.05 were considered statistically significant.

RESULTS: No significant differences were found in maternal and perinatal outcomes between groups. Neither were differences observed in pregnancy prolongation (mean: 8.42days (SD±7.462) in group A and 10.5days (SD±8.235) in group B (p=0.391)). At the start of expectant management, 31.8% of fetuses had an abnormal middle cerebral artery Doppler; prior to delivery, this percentage was 77.4%.

CONCLUSION: Pregnant women with severe early-onset preeclampsia and associated risk factors benefited from expectant management. During expectant management using a continuous magnesium sulfate regimen, the majority of fetuses showed cerebral vasodilatation. The exact clinical value of this finding should be clarified in further studies.

Copyright © 2013 International Society for the Study of Hypertension in Pregnancy. Published by Elsevier B.V. All rights reserved.

Keywords: Eclampsia; Expectant management; HELLP syndrome; Magnesium sulfate; Risk factors; Severe preeclampsia

Publication Types