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Pregnancy Hypertens. 2011 Apr;1(2):185-9. doi: 10.1016/j.preghy.2011.01.001. Epub 2011 Feb 01.

Antihypertensive drug prescription pattern before and during pregnancy in France.

Pregnancy hypertension

Veronique Duhalde, Caroline Delarue, Isabelle Lacroix, Carole Suarez, Robert Bourrel, Jean-Louis Montastruc, Christine Damase-Michel

Affiliations

  1. Laboratoire de Pharmacologie Médicale et Clinique, Unité de Pharmacoépidémiologie, EA 3696, Université de Toulouse, Faculté de Médecine, 37 allées Jules-Guesde, 31000 Toulouse, France.
  2. Caisse Régionale d'Assurance Maladie de Midi-Pyrénées, 31065 Toulouse Cedex 9, France.

PMID: 26104501 DOI: 10.1016/j.preghy.2011.01.001

Abstract

OBJECTIVE: This study provides firsthand information on antihypertensive prescriptions before and during pregnancy in France.

METHODS: The study, on 23,898 women, was carried out using data from the French Health Insurance System.

RESULTS: Before and during pregnancy, 1.1% and 5.1% of women received prescriptions for antihypertensive drugs: beta blockers and diuretics before, and nifedipine, nicardipine, labetalol and methyldopa during pregnancy. Sixty-six pregnant women were exposed to angiotensin-converting enzyme inhibitors and angiotensin II receptor antagonists.

CONCLUSION: Pregnant women still receive prescriptions for harmful drugs. In order to prevent such exposures, it should be recommended to avoid these prescriptions in women of child-bearing age who plan to be pregnant.

Copyright © 2011 International Society for the Study of Hypertension in Pregnancy. Published by Elsevier B.V. All rights reserved.

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