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Kamper L, Haage P, Brandt AS, et al. Diffusion-weighted MRI in the follow-up of chronic periaortitis. Br J Radiol. 2015;88(1052):20150145doi: 10.1259/bjr.20150145.
Kamper, L., Haage, P., Brandt, A. S., Piroth, W., Abanador-Kamper, N., Roth, S., & Ekamp, H. (2015). Diffusion-weighted MRI in the follow-up of chronic periaortitis. The British journal of radiology, 88(1052), 20150145. https://doi.org/10.1259/bjr.20150145
Kamper, L, et al. "Diffusion-weighted MRI in the follow-up of chronic periaortitis." The British journal of radiology vol. 88,1052 (2015): 20150145. doi: https://doi.org/10.1259/bjr.20150145
Kamper L, Haage P, Brandt AS, Piroth W, Abanador-Kamper N, Roth S, Ekamp H. Diffusion-weighted MRI in the follow-up of chronic periaortitis. Br J Radiol. 2015 Aug;88(1052):20150145. doi: 10.1259/bjr.20150145. Epub 2015 May 29. PMID: 26023949.
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Br J Radiol. 2015 Aug;88(1052):20150145. doi: 10.1259/bjr.20150145. Epub 2015 May 29.

Diffusion-weighted MRI in the follow-up of chronic periaortitis.

The British journal of radiology

L Kamper, P Haage, A S Brandt, W Piroth, N Abanador-Kamper, S Roth, H Ekamp

Affiliations

  1. 1 Department of Diagnostic and Interventional Radiology, HELIOS Klinikum Wuppertal, University Hospital Witten/Herdecke, Wuppertal, Germany.
  2. 2 Department of Urology, HELIOS Klinikum Wuppertal, University Hospital Witten/Herdecke, Wuppertal, Germany.
  3. 3 Department of Cardiology, HELIOS Klinikum Wuppertal, University Hospital Witten/Herdecke, Arrenberger Straße, Wuppertal, Germany.

PMID: 26023949 DOI: 10.1259/bjr.20150145

Abstract

OBJECTIVE:: To evaluate the usefulness of diffusion-weighted MRI (DWI) for the assessment of the intraindividual follow-up in patients with chronic periaortitis (CP) under medication.

METHODS:: MRI data of 21 consecutive patients with newly diagnosed untreated disease were retrospectively examined before and after medical therapy, with a median follow-up of 16 weeks. DWI parameters [b800 signal, apparent diffusion coefficient (ADC) values] of the CP and psoas muscle were analysed together with the extent and contrast enhancement. Pre- and post-treatment laboratory inflammation markers were acquired parallel to each MR examination.

RESULTS:: Statistically significant lower b800 signal intensities (p ≤ 0.0001) and higher ADC values (p ≤ 0.0001) were observed after medical treatment within the fibrous periaortic tissue. Extent and contrast enhancement of the CP showed also a statistically significant decrease (p ≤ 0.0001) in the follow-up examinations, while the control parameters within the psoas muscle showed no differences.

CONCLUSION:: DWI seems to be a useful method for the evaluation of response to treatment without contrast agents. The technique may be helpful in the assessment of disease activity to guide further therapeutic strategies.

ADVANCES IN KNOWLEDGE:: DWI detects significant differences in the intraindividual follow-up of CP under medical therapy.

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