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Righi A, Gambarotti M, Sbaraglia M, et al. Metastasizing tenosynovial giant cell tumour, diffuse type/pigmented villonodular synovitis. Clin Sarcoma Res. 2015;5:15doi: 10.1186/s13569-015-0030-2.
Righi, A., Gambarotti, M., Sbaraglia, M., Frisoni, T., Donati, D., Vanel, D., & Dei Tos, A. P. (2015). Metastasizing tenosynovial giant cell tumour, diffuse type/pigmented villonodular synovitis. Clinical sarcoma research, 515. https://doi.org/10.1186/s13569-015-0030-2
Righi, A, et al. "Metastasizing tenosynovial giant cell tumour, diffuse type/pigmented villonodular synovitis." Clinical sarcoma research vol. 5 (2015): 15. doi: https://doi.org/10.1186/s13569-015-0030-2
Righi A, Gambarotti M, Sbaraglia M, Frisoni T, Donati D, Vanel D, Dei Tos AP. Metastasizing tenosynovial giant cell tumour, diffuse type/pigmented villonodular synovitis. Clin Sarcoma Res. 2015 Jun 06;5:15. doi: 10.1186/s13569-015-0030-2. eCollection 2015. PMID: 26052431; PMCID: PMC4458002.
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Clin Sarcoma Res. 2015 Jun 06;5:15. doi: 10.1186/s13569-015-0030-2. eCollection 2015.

Metastasizing tenosynovial giant cell tumour, diffuse type/pigmented villonodular synovitis.

Clinical sarcoma research

A Righi, M Gambarotti, M Sbaraglia, T Frisoni, D Donati, D Vanel, A P Dei Tos

Affiliations

  1. Department of Pathology, Istituto Ortopedico Rizzoli, Via del Barbiano 1/10, 40136 Bologna, Italy.
  2. Department of Pathology, Treviso Regional Hospital, Treviso, Italy.
  3. Oncologic Department, Rizzoli Orthopaedic Institute, Bologna, Italy.
  4. Department of Pathology, Istituto Ortopedico Rizzoli, Via del Barbiano 1/10, 40136 Bologna, Italy ; Department of Pathology, Treviso Regional Hospital, Treviso, Italy.

PMID: 26052431 PMCID: PMC4458002 DOI: 10.1186/s13569-015-0030-2

Abstract

Tenosynovial giant cell tumour, diffuse type, also known under a variety of other terms including diffuse pigmented villonodular synovitis, tends to be locally aggressive and not infrequently can show multiple recurrences. The differential diagnosis with the extremely rare and somewhat controversial malignant variant of tenosynovial giant cell tumour, diffuse type, is challenging due to overlapping radiologic features of these two entities. Malignant tenosynovial giant cell tumour is defined by the presence of overtly malignant sarcomatous areas. We describe a very unusual case of a 63-year-old man affected by tenosynovial giant cell tumour, diffuse type of the knee that, despite absence of morphologic evidence of sarcomatous transformation, developed inguinal lymph node metastases following multiple surgical procedures.

Keywords: Diffuse type; Lymph node; Metastases; Tenosynovial giant cell tumor

References

  1. Arch Pathol Lab Med. 1999 Oct;123(10):960-2 - PubMed
  2. Am J Surg Pathol. 2008 Apr;32(4):587-99 - PubMed
  3. J Bone Joint Surg Br. 1998 Jan;80(1):43-7 - PubMed
  4. Am J Surg Pathol. 1997 Feb;21(2):153-63 - PubMed
  5. J Bone Joint Surg Br. 2007 Nov;89(11):1504-8 - PubMed
  6. Radiographics. 2008 Sep-Oct;28(5):1493-518 - PubMed
  7. Open Orthop J. 2011 Jan 07;5:13-6 - PubMed
  8. Am J Surg Pathol. 2000 Apr;24(4):479-92 - PubMed
  9. Int J Oncol. 2014 May;44(5):1425-32 - PubMed
  10. Hum Pathol. 2014 Nov;45(11):2355-8 - PubMed

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