Display options
Share it on

Cardiol Res Pract. 2015;2015:528753. doi: 10.1155/2015/528753. Epub 2015 May 28.

Factors Associated with the Use of Drug-Eluting Stents in Patients Presenting with Acute ST-Segment Elevation Myocardial Infarction.

Cardiology research and practice

Jose F Chavez, Jacob A Doll, Anuj Mediratta, Francesco Maffessanti, Janet Friant, Jonathan D Paul, John E A Blair, Sandeep Nathan, Neeraj Jolly, Atman P Shah

Affiliations

  1. Section of Cardiology, Department of Medicine, The University of Chicago Medical Center, 5841 S. Maryland Avenue, Chicago, IL 60637, USA.
  2. Section of Cardiology, Department of Medicine, Rush University Medical Center, 1653 W. Congress Parkway, Chicago, IL 60612, USA.

PMID: 26106504 PMCID: PMC4464005 DOI: 10.1155/2015/528753

Abstract

Background. Drug-eluting stents (DES) have proven clinical superiority to bare-metal stents (BMS) for the treatment of patients with ST-segment elevation myocardial infarction (STEMI). Decision to implant BMS or DES is dependent on the patient's ability to take dual antiplatelet therapy. This study investigated factors associated with DES placement in STEMI patients. Methods. Retrospective analysis was performed on 193 patients who presented with STEMI and were treated with percutaneous coronary intervention at an urban, tertiary care hospital. Independent factors associated with choice of stent type were determined using stepwise multivariate logistic regression. Odds ratio (OR) was used to evaluate factors significantly associated with DES and BMS. Results. 128 received at least one DES, while 65 received BMS. BMS use was more likely in the setting of illicit drug or alcohol abuse ([OR] 0.15, 95% CI 0.05-0.48, p ≤ 0.01), cardiogenic shock (OR 0.26, 95% CI 0.10-0.73, p = 0.01), and larger stent diameter (OR 0.28, 95% CI 0.11-0.68, p ≤ 0.01). Conclusions. In this analysis, BMS implantation was associated with illicit drug or alcohol abuse and presence of cardiogenic shock. This study did not confirm previous observations that non-White race, insurance, or income predicts BMS use.

References

  1. Arch Intern Med. 2000 May 8;160(9):1329-35 - PubMed
  2. Ann Intern Med. 2001 Sep 4;135(5):352-66 - PubMed
  3. J Natl Med Assoc. 2002 Aug;94(8):666-8 - PubMed
  4. Circulation. 2003 Jul 22;108(3):286-91 - PubMed
  5. Catheter Cardiovasc Interv. 2004 May;62(1):1-17 - PubMed
  6. Circulation. 2005 Mar 15;111(10):1225-32 - PubMed
  7. Case Manager. 2005 Mar-Apr;16(2):47-51 - PubMed
  8. JAMA. 2005 May 4;293(17):2126-30 - PubMed
  9. N Engl J Med. 2005 Aug 4;353(5):487-97 - PubMed
  10. Circulation. 2006 Jun 20;113(24):2803-9 - PubMed
  11. Am J Cardiol. 2006 Aug 1;98(3):352-6 - PubMed
  12. Am Heart J. 2006 Aug;152(2):321-6 - PubMed
  13. JAMA. 2007 Jan 10;297(2):159-68 - PubMed
  14. J Am Coll Cardiol. 2006 Dec 19;48(12):2584-91 - PubMed
  15. Am J Cardiol. 2007 Oct 15;100(8):1192-8 - PubMed
  16. Am Heart J. 2008 Dec;156(6):1133-40 - PubMed
  17. Am J Cardiol. 2009 Mar 1;103(5):653-8 - PubMed
  18. JACC Cardiovasc Interv. 2008 Oct;1(5):494-503 - PubMed
  19. Circulation. 2009 Jun 30;119(25):3198-206 - PubMed
  20. Transl Res. 2009 Aug;154(2):78-89 - PubMed
  21. Am Heart J. 2009 Oct;158(4):e43-50 - PubMed
  22. Circulation. 2010 Jun 1;121(21):2294-301 - PubMed
  23. JACC Cardiovasc Interv. 2010 Jul;3(7):773-9 - PubMed
  24. Am J Cardiol. 2011 Mar 1;107(5):685-9 - PubMed
  25. Am J Cardiol. 2011 Mar 1;107(5):675-80 - PubMed
  26. J Am Coll Cardiol. 2011 Dec 6;58(24):e44-122 - PubMed
  27. Circulation. 2012 Jun 12;125(23):2873-91 - PubMed
  28. Circulation. 2013 Jan 29;127(4):e362-425 - PubMed
  29. Circulation. 2013 Apr 2;127(13):1395-403 - PubMed
  30. Cardiovasc Revasc Med. 2014 Jun;15(4):214-8 - PubMed

Publication Types

Grant support