Iran J Otorhinolaryngol. 2015 May;27(80):179-84.
Prophylactic Effects of Lidocaine or Beclomethasone Spray on Post-Operative Sore Throat and Cough after Orotracheal Intubation.
Iranian journal of otorhinolaryngology
Nadia Banihashem, Ebrahim Alijanpour, Bahman Hasannasab, Ali Zarei
Affiliations
Affiliations
- Department of Anesthesiology, Babol University of Medical Sciences, Babol, Iran.
PMID: 26082898
PMCID: PMC4461840
Abstract
INTRODUCTION: Post-operative sore throat and cough are common complications of endotracheal intubation. These conditions may be very distressing for the patient and may lead to unpleasant memories. This study was performed in order to determine whether beclomethasone and lidocaine spray could reduce the frequency of post-operative sore throat and hoarseness after tracheal extubation.
MATERIALS AND METHODS: Ninety women (18-60 years of age) with an American Society of Anesthesiologists (ASA) physical status I or II and undergoing elective mastoidectomy were randomized into three groups of 30 patients. The endotracheal tubes in each group were sprayed with 50% beclomethasone, 10% lidocaine hydrochloride, or normal saline (control group) before endotracheal intubation. Patients were examined for sore throat (none, mild, moderate, or severe), cough, and hoarseness at 1 and 24 h after extubation.
RESULTS: There was a significantly lower incidence and severity of post-operative sore throat in the beclomethasone group than the lidocaine and control groups (P<0.05) at each observation time point. At 24 h after extubation, the incidence and severity of sore throat and cough was significantly lower in the lidocaine compared with the control group. The incidence of hoarseness was not significantly different among the three groups.
CONCLUSION: Spraying beclomethasone and lidocaine on the endotracheal tube is a simple and effective method to reduce the incidence and severity of post-operative sore throat.
Keywords: Beclomethasone; Lidocaine; Sore throat
References
- Can J Anaesth. 2007 Nov;54(11):897-901 - PubMed
- J Anesth. 2004;18(4):237-40 - PubMed
- J Anesth. 2006;20(1):44-7 - PubMed
- Anesth Analg. 2006 Oct;103(4):1001-3 - PubMed
- Br J Anaesth. 2008 Feb;100(2):215-8 - PubMed
- Acta Anaesthesiol Scand. 1993 Apr;37(3):250-2 - PubMed
- Iran J Otorhinolaryngol. 2013 Sep;25(73):215-20 - PubMed
- Anesth Analg. 2004 Oct;99(4):1253-7, table of contents - PubMed
- Acta Anaesthesiol Scand. 2010 Feb;54(2):147-53 - PubMed
- Middle East J Anaesthesiol. 2012 Feb;21(4):513-9 - PubMed
- J Dent. 2009 Feb;37(2):93-7 - PubMed
- Sao Paulo Med J. 2007 Nov 1;125(6):322-8 - PubMed
- Anesth Analg. 2010 Oct;111(4):882-6 - PubMed
- Ann Saudi Med. 2008 Jan-Feb;28(1):11-6 - PubMed
- AANA J. 2012 Aug;80(4 Suppl):S67-73 - PubMed
- Anesth Analg. 1985 Dec;64(12):1189-92 - PubMed
- Indian J Anaesth. 2009 Feb;53(1):40-3 - PubMed
- Anesth Analg. 2010 Oct;111(4):895-8 - PubMed
- Anesthesiology. 2000 Sep;93(3):858-75 - PubMed
- J Anesth. 2010 Dec;24(6):962-5 - PubMed
- Burns. 2003 Jun;29(4):335-41 - PubMed
- Anaesthesia. 1990 Nov;45(11):968-71 - PubMed
- Middle East J Anaesthesiol. 2007 Feb;19(1):197-204 - PubMed
- Anesth Analg. 2008 Dec;107(6):1814-8 - PubMed
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