Display options
Cite
Jonas JB, Budde WM, Stroux A, et al. Diurnal Intraocular Pressure Profiles in Chronic Open-Angle Glaucoma. Asia Pac J Ophthalmol (Phila). 2012;1(2):84-7doi: 10.1097/APO.0b013e31823e4cb0.
Jonas, J. B., Budde, W. M., Stroux, A., Oberacher-Velten, I. M., & Jünemann, A. (2012). Diurnal Intraocular Pressure Profiles in Chronic Open-Angle Glaucoma. Asia-Pacific journal of ophthalmology (Philadelphia, Pa.), 1(2), 84-7. https://doi.org/10.1097/APO.0b013e31823e4cb0
Jonas, Jost B, et al. "Diurnal Intraocular Pressure Profiles in Chronic Open-Angle Glaucoma." Asia-Pacific journal of ophthalmology (Philadelphia, Pa.) vol. 1,2 (2012): 84-7. doi: https://doi.org/10.1097/APO.0b013e31823e4cb0
Jonas JB, Budde WM, Stroux A, Oberacher-Velten IM, Jünemann A. Diurnal Intraocular Pressure Profiles in Chronic Open-Angle Glaucoma. Asia Pac J Ophthalmol (Phila). 2012 Mar-Apr;1(2):84-7. doi: 10.1097/APO.0b013e31823e4cb0. PMID: 26107128.
Copy Download .nbib Format: NLM
Share it on

Asia Pac J Ophthalmol (Phila). 2012 Mar-Apr;1(2):84-7. doi: 10.1097/APO.0b013e31823e4cb0.

Diurnal Intraocular Pressure Profiles in Chronic Open-Angle Glaucoma.

Asia-Pacific journal of ophthalmology (Philadelphia, Pa.)

Jost B Jonas, Wido M Budde, Andrea Stroux, Isabel M Oberacher-Velten, Anselm Jünemann

Affiliations

  1. From the *Department of Ophthalmology, Faculty of Clinical Medicine Mannheim, University of Heidelberg, Mannheim; †Department of Ophthalmology, University Erlangen-Nürnberg, Erlangen; and ‡Department of Medical Informatics, Biometry and Epidemiology, Campus Benjamin Franklin, Charité Berlin, Berlin, Germany.

PMID: 26107128 DOI: 10.1097/APO.0b013e31823e4cb0

Abstract

PURPOSE: To evaluate day-and-night intraocular pressure (IOP) profiles in normal and glaucomatous eyes.

DESIGN: Hospital-based clinical observational study.

METHODS: The study included 3561 day-and-night profiles of IOP measurements performed by Goldmann applanation tonometry on 1408 eyes of 720 normal Caucasian subjects or chronic open-angle glaucoma patients.

RESULTS: For all groups except the secondary open-angle glaucoma group, IOP was highest at 7 a.m., followed by noon and 5 p.m., and finally at 9 p.m. or midnight. In secondary open-angle glaucoma, mean measurements did not vary significantly during day and night. The profile amplitude (mean: 5.5 2.8 mm Hg) was significantly (P < 0.001) higher in the secondary open-angle glaucoma group than in the normal-pressure glaucoma group and the normal group. The two latter groups did not vary significantly (P = 0.47) in profile amplitude. Expressed as percentage of the mean IOP, the IOP amplitude did not vary significantly between any of the study groups. The inter-eye IOP difference for any measurement time was significantly (P < 0.001) smaller than the IOP profile amplitude.

CONCLUSIONS: Treated secondary open-angle glaucoma eyes did not exhibit the normal day-and-night pressure profile which was usually shown in normal eyes and eyes treated for other types of chronic open-angle glaucoma. The day-and-night IOP amplitude in absolute terms is highest in secondary open-angle glaucoma. In relative terms, the IOP amplitude did not vary significantly between the various types of chronic open-angle glaucoma. Inter-eye IOP differences were significantly (P < 0.001) smaller than the IOP profile amplitude.

Publication Types