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Rev Urol. 2015;17(1):38-41.

Adenocarcinoma of the urethra with mucinous features.

Reviews in urology

Arthi Satyanarayan, Lucas Redd, Anthony Dyer, Andrew Wright, Jonathan Walker

Affiliations

  1. The University of Arizona College of Medicine, Tucson, AZ.
  2. Department of Pathology, The University of Arizona Medical Center, Tucson, AZ.
  3. Division of Urology, The University of Arizona Medical Center, Tucson, AZ.

PMID: 26029002 PMCID: PMC4444775

Abstract

Primary adenocarcinoma of the female urethra is a rare malignancy. Previous studies hypothesize multiple origins, including periurethral glands or intestinal metaplasia. We report a case of a 60-year-old white woman with adenocarcinoma of the urethra who initially presented with obstructive voiding complaints secondary to a urethral mass. Wide local excision revealed invasive adenocarcinoma of the urethra with mucinous features. There was intestinal metaplasia adjacent to the tumor, as well as separate identification of intestinal metaplasia along the urethra. Ultimately, the patient underwent radical cystectomy with ileal conduit urinary diversion with no evidence of recurrence, indicating the role of early identification and surgical intervention for such cases.

Keywords: Genital tract tumor; Radical cystectomy; Skene gland; Urethra; Urethral adenocarcinoma

References

  1. Case Rep Med. 2013;2013:387591 - PubMed
  2. J Urol. 1999 Jun;161(6):1881-4 - PubMed
  3. Urol Oncol. 2011 Mar-Apr;29(2):218-23 - PubMed
  4. Urol Oncol. 2004 Sep-Oct;22(5):404-9 - PubMed
  5. Int J Clin Exp Pathol. 2013 Jul 15;6(8):1665-70 - PubMed
  6. Urol Clin North Am. 2010 Aug;37(3):445-57 - PubMed
  7. Gynecol Oncol. 1995 Dec;59(3):352-7 - PubMed
  8. Am J Pathol. 2014 Mar;184(3):584-91 - PubMed
  9. Oncol Lett. 2012 Nov;4(5):951-954 - PubMed
  10. Korean J Pathol. 2012 Apr;46(2):210-4 - PubMed
  11. Can J Urol. 2010 Oct;17(5):5404-7 - PubMed

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