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J Phys Ther Sci. 2015 Apr;27(4):1117-20. doi: 10.1589/jpts.27.1117. Epub 2015 Apr 30.

Blood levels related to the Z-score of bone mineral density in young males and females.

Journal of physical therapy science

Sun-Hyung Joo, Min-Tae Kim, Jae-Hwan Cho, Hae-Kag Lee, Jae-Ouk Ahn

Affiliations

  1. Department of Internal Medicine, Dongdaemun Health Center, Republic of Korea.
  2. Department of Radiology, Kyung Hee University Hospital at Gang-dong, Republic of Korea ; Department of International Radiological Science, Hallym University of Graduate Studies, Republic of Korea.
  3. Department of International Radiological Science, Hallym University of Graduate Studies, Republic of Korea.
  4. Department of Computer Science and Engineering, Soonchunhyang University, Republic of Korea.
  5. Department of Medical IT Engineering, Soonchunhyang University: Asan, Chungnam 336-745, Republic of Korea.

PMID: 25995569 PMCID: PMC4433990 DOI: 10.1589/jpts.27.1117

Abstract

[Purpose] The purpose of this study was to investigate the blood levels related to the bone mineral density by using the dual energy X-ray absorption for females before menopause and males younger than 50 years old. [Subjects and Methods] Between August 1, and September 15, 2013, the Z-score was measured in females before menopause and males younger than 50 years old using a bone mineral density measuring instrument. After the measurement, the subjects were classified into two groups, that is, the below expectations and within expectations groups. Next, we analyzed and compared the differences in age, body mass index, and blood levels between the 2 groups. [Results] The results showed a correlation of 0.212 for total protein, -0.317 for alanine aminotransferase, -0.199 for gamma-glutamyl transferase, -0.358 for alkaline phosphatase, 0.266 for uric acid, -0.313 for lactate dehydrogenase, 0.244 for creatinine, -0.234 for the red blood cell count, and -0.230 for the red cell distribution width in patients with less than expected level for their age. [Conclusion] In conclusion, osteoporosis may occur in females before menopause and males younger than 50 years old, and aggressive attention is required for prevention and treatment.

Keywords: Blood levels; Bone mineral density; Z-score

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