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J Phys Ther Sci. 2015 Apr;27(4):1243-6. doi: 10.1589/jpts.27.1243. Epub 2015 Apr 30.

The relationship between breast density and bone mineral density after menopause.

Journal of physical therapy science

Jae-Hwan Cho, Ji-Hye Kim, Hae-Kag Lee

Affiliations

  1. Department of International Radiological Science, Hallym University of Graduate Studies, Republic of Korea.
  2. Department of International Radiological Science, Hallym University of Graduate Studies, Republic of Korea ; Department of Radiology, Soonchunhyang University Hospital, Republic of Korea.
  3. Department of Computer Science and Engineering, Soonchunhyang University, Republic of Korea.

PMID: 25995598 PMCID: PMC4434019 DOI: 10.1589/jpts.27.1243

Abstract

[Purpose] The purpose of this study was to analyze the relationship between breast density and bone mineral density after menopause. [Subjects and Methods] The subjects were 130 patients who participated in a bone densitometry test and had a mammogram taken between January 1st, 2013 to October 1st, 2014. The mammograms were scored breast imaging-reporting and data system. Grade 1 indicates almost only fat, Grade 2 indicates fibroglandular densities, Grade 3 indicates heterogeneously dense tissue, and Grade 4 indicates an extreme density. Correlation analysis was carried out to investigate the relationship between breast density grades and bone mineral densities by age and body mass index. [Results] Breast density had a close relationship with age (-0.59), Body mass index (-0.39), and T-score (0.29). The results indicate that as age and body mass index increase, the grade of the breast density decreases, and as the T-score increases, the grade increases. [Conclusion] A precise evaluation of the of breast cancer risk associated with breast density should be conducted as a large scale prospective study for women in Korea.

Keywords: Bone mineral density; Breast density

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