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Nanoscale Res Lett. 2014 Dec;9(1):2361. doi: 10.1186/1556-276X-9-623. Epub 2014 Nov 21.

Soft UV nanoimprint lithography-designed highly sensitive substrates for SERS detection.

Nanoscale research letters

Maximilien Cottat, Nathalie Lidgi-Guigui, Inga Tijunelyte, Grégory Barbillon, Frédéric Hamouda, Philippe Gogol, Abdelhanin Aassime, Jean-Michel Lourtioz, Bernard Bartenlian, Marc Lamy de la Chapelle

Affiliations

  1. CSPBAT (UMR 7244), CNRS-Université Paris 13, 74 rue Marcel Cachin, 93017, Bobigny, France, [email protected].

PMID: 26089008 PMCID: PMC4494019 DOI: 10.1186/1556-276X-9-623

Abstract

We report on the use of soft UV nanoimprint lithography (UV-NIL) for the development of reproducible, millimeter-sized, and sensitive substrates for SERS detection. The used geometry for plasmonic nanostructures is the cylinder. Gold nanocylinders (GNCs) showed to be very sensitive and specific sensing surfaces. Indeed, we demonstrated that less than 4 ×10(6) avidin molecules were detected and contributed to the surface-enhanced Raman scattering (SERS) signal. Thus, the soft UV-NIL technique allows to obtain quickly very sensitive substrates for SERS biosensing on surfaces of 1 mm (2).

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