Display options
Share it on

Genome Announc. 2015 Jun 18;3(3). doi: 10.1128/genomeA.00639-15.

Molecular Characterization of the First Ebola Virus Isolated in Italy, from a Health Care Worker Repatriated from Sierra Leone.

Genome announcements

Concetta Castilletti, Fabrizio Carletti, Cesare E M Gruber, Licia Bordi, Eleonora Lalle, Serena Quartu, Silvia Meschi, Daniele Lapa, Francesca Colavita, Roberta Chiappini, Antonio Mazzarelli, Patrizia Marsella, Nicola Petrosillo, Emanuele Nicastri, Giovanni Chillemi, Alessio Valentini, Alessandro Desideri, Antonino Di Caro, Giuseppe Ippolito, Maria R Capobianchi

Affiliations

  1. National Institute for Infectious Diseases L. Spallanzani, Rome, Italy.
  2. CINECA, Rome, Italy.
  3. National Institute for Infectious Diseases L. Spallanzani, Rome, Italy [email protected].

PMID: 26089420 PMCID: PMC4472897 DOI: 10.1128/genomeA.00639-15

Abstract

Here, we report the complete genome sequence of an Ebola virus (EBOV) isolated from a health worker repatriated from Sierra Leone to Italy in November 2014. The sequence, clustering in clade 3 of the Sierra Leone sequences, was analyzed with respect to mutations possibly affecting diagnostic and therapeutic targets as well as virulence.

Copyright © 2015 Castilletti et al.

References

  1. Sci Transl Med. 2013 Aug 21;5(199):199ra113 - PubMed
  2. Biosecur Bioterror. 2011 Dec;9(4):361-71 - PubMed
  3. Nature. 2014 Oct 2;514(7520):47-53 - PubMed
  4. Proc Natl Acad Sci U S A. 2012 Oct 30;109(44):18030-5 - PubMed
  5. Lancet. 2010 May 29;375(9729):1896-905 - PubMed
  6. Nat Med. 2010 Sep;16(9):991-4 - PubMed
  7. MBio. 2015 Jan 20;6(1):null - PubMed
  8. Zoonoses Public Health. 2012 Sep;59 Suppl 2:151-7 - PubMed
  9. Science. 2015 Apr 3;348(6230):117-9 - PubMed
  10. Proc Natl Acad Sci U S A. 2012 Mar 27;109(13):5034-9 - PubMed
  11. J Clin Microbiol. 2007 Jan;45(1):224-6 - PubMed
  12. N Engl J Med. 2014 Oct 9;371(15):1418-25 - PubMed
  13. J Clin Virol. 2015 Jan;62:124-34 - PubMed
  14. Science. 2014 Sep 12;345(6202):1369-72 - PubMed
  15. Genome Biol. 2014;15(11):540 - PubMed
  16. Sci Rep. 2013 Nov 28;3:3365 - PubMed
  17. Bull World Health Organ. 1978;56(2):271-93 - PubMed
  18. Front Microbiol. 2013 Sep 05;4:267 - PubMed

Publication Types