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Int J Angiol. 2015 Jun;24(2):93-8. doi: 10.1055/s-0034-1396341.

Effects of Gender on Outcomes and Survival Following Repair of Acute Type A Aortic Dissection.

The International journal of angiology : official publication of the International College of Angiology, Inc

Brian D Conway, Sotiris C Stamou, Nicholas T Kouchoukos, Kevin W Lobdell, Robert C Hagberg

Affiliations

  1. Department of Cardiothoracic Surgery, University of Iowa Hospitals and Clinics, Iowa City, Iowa.
  2. Division of Cardiothoracic Surgery, Missouri Baptist Medical Center, Saint Louis, Missouri.
  3. Department of Thoracic and Cardiovascular Surgery, Sanger Heart and Vascular Institute, Carolinas Medical Center, Charlotte, North Carolina.
  4. Department of Cardiac Surgery, Hartford Hospital, Hartford, Connecticut.

PMID: 26060379 PMCID: PMC4452609 DOI: 10.1055/s-0034-1396341

Abstract

Previous studies have demonstrated gender-related differences in early and late outcomes following type A dissection diagnosis. However, it is widely unknown whether gender affects early clinical outcomes and survival after repair of type A aortic dissection. The goal of this study was to compare the early and late clinical outcomes in women versus men after repair of acute type A aortic dissections. Between January 2000 and October 2010 a total of 251 patients from four academic medical centers underwent repair of acute type A aortic dissection. Of those, 79 were women and 172 were men with median ages of 67 (range, 20-87 years) and 58 years (range, 19-83 years), respectively (p < 0.001). Major morbidity, operative mortality, and 10-year actuarial survival were compared between the groups. Operative mortality was not significantly influenced by gender (19% for women vs. 17% for men, p = 0.695). There were similar rates of hemodynamic instability (12% for women vs. 13% men, p = 0.783) between the two groups. Actuarial 10-year survival rates were 58% for women versus 73% for men (p = 0.284). Gender does not significantly impact early clinical outcomes and actuarial survival following repair of acute type A aortic dissection.

Keywords: aortic dissection; cardiac surgery; dissection; repair

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