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Genome Announc. 2015 May 21;3(3). doi: 10.1128/genomeA.00513-15.

Draft Genome Sequence of New Leprosy Agent Mycobacterium lepromatosis.

Genome announcements

Xiang Y Han, Nipun A Mistry, Erika J Thompson, Hong-Li Tang, Kanhav Khanna, Li Zhang

Affiliations

  1. Department of Laboratory Medicine, The University of Texas M. D. Anderson Cancer Center, Houston, Texas, USA [email protected].
  2. Department of Bioinformatics, The University of Texas M. D. Anderson Cancer Center, Houston, Texas, USA.
  3. Sequencing and Microarray Facility, The University of Texas M. D. Anderson Cancer Center, Houston, Texas, USA.

PMID: 25999555 PMCID: PMC4440969 DOI: 10.1128/genomeA.00513-15

Abstract

Mycobacterium lepromatosis is a newly discovered cause of leprosy. Here, we present a near-complete genome of M. lepromatosis from strain FJ924 obtained from a patient who died of leprosy. The genome contained 3,215,823 nucleotides and matched ~87% with the Mycobacterium leprae genome. This genome is likely the smallest of all mycobacterial genomes known to date.

Copyright © 2015 Han et al.

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