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Liang X, Kundu P, Finlay J, et al. Maximizing fluence rate and field uniformity of light blanket for intraoperative PDT. Proc SPIE Int Soc Opt Eng. 2012;8210doi: 10.1117/12.908493.
Liang, X., Kundu, P., Finlay, J., Goodwin, M., & Zhu, T. C. (2012). Maximizing fluence rate and field uniformity of light blanket for intraoperative PDT. Proceedings of SPIE--the International Society for Optical Engineering, 8210. https://doi.org/10.1117/12.908493
Liang, Xing, et al. "Maximizing fluence rate and field uniformity of light blanket for intraoperative PDT." Proceedings of SPIE--the International Society for Optical Engineering vol. 8210 (2012). doi: https://doi.org/10.1117/12.908493
Liang X, Kundu P, Finlay J, Goodwin M, Zhu TC. Maximizing fluence rate and field uniformity of light blanket for intraoperative PDT. Proc SPIE Int Soc Opt Eng. 2012 Jan 21;8210. doi: 10.1117/12.908493. PMID: 25999639; PMCID: PMC4437740.
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Proc SPIE Int Soc Opt Eng. 2012 Jan 21;8210. doi: 10.1117/12.908493.

Maximizing fluence rate and field uniformity of light blanket for intraoperative PDT.

Proceedings of SPIE--the International Society for Optical Engineering

Xing Liang, Palak Kundu, Jarod Finlay, Michael Goodwin, Timothy C Zhu

Affiliations

  1. Department of Radiation Oncology, University of Pennsylvania, 3400 Civic Center Boulevard, Philadelphia, PA, USA 19104.

PMID: 25999639 PMCID: PMC4437740 DOI: 10.1117/12.908493

Abstract

A light blanket is designed with a system of cylindrically diffusing optical fibers, which are spirally oriented. This 25×30 cm rectangular light blanket is capable of providing uniform illumination during intraoperative photodynamic therapy. The flexibility of the blanket proves to be extremely beneficial when conforming to the anatomical structures of the patient being treated. Previous tests of light distribution from the blanket have shown significant loss of intensity with the length of the fiber. This can be improved through the use of an optical adaptor which will be able to match the numerical aperture of the laser source to the numerical aperture of the blanket fiber; thus transmitting a higher percentage of light.

Keywords: Light blanket; Photodynamic therapy; intraoperative PDT

References

  1. Proc SPIE Int Soc Opt Eng. 2013 Jul 13;7380:73801W - PubMed
  2. Proc SPIE Int Soc Opt Eng. 2010 Jan 23;7551:null - PubMed

Publication Types

Grant support