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Fischer AS, Møller BK, Krag S, et al. Influenza virus vaccination and kidney graft rejection: causality or coincidence. Clin Kidney J. 2015;8(3):325-8doi: 10.1093/ckj/sfv027.
Fischer, A. S., Møller, B. K., Krag, S., Jespersen, B., & Hewett, J. P. (2015). Influenza virus vaccination and kidney graft rejection: causality or coincidence. Clinical kidney journal, 8(3), 325-8. https://doi.org/10.1093/ckj/sfv027
Fischer, Anne Sophie Lind, et al. "Influenza virus vaccination and kidney graft rejection: causality or coincidence." Clinical kidney journal vol. 8,3 (2015): 325-8. doi: https://doi.org/10.1093/ckj/sfv027
Fischer AS, Møller BK, Krag S, Jespersen B, Hewett JP. Influenza virus vaccination and kidney graft rejection: causality or coincidence. Clin Kidney J. 2015 Jun;8(3):325-8. doi: 10.1093/ckj/sfv027. Epub 2015 May 06. PMID: 26034595; PMCID: PMC4440474.
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Clin Kidney J. 2015 Jun;8(3):325-8. doi: 10.1093/ckj/sfv027. Epub 2015 May 06.

Influenza virus vaccination and kidney graft rejection: causality or coincidence.

Clinical kidney journal

Anne Sophie Lind Fischer, Bjarne Kuno Møller, Søren Krag, Bente Jespersen, Hewett

Affiliations

  1. Department of Nephrology , Aarhus University Hospital, Skejby , Århus N DK-8200 , Denmark.
  2. Department of Clinical Immunology , Aarhus University Hospital, Skejby , Aarhus N DK-8200 , Denmark.
  3. Department of Pathology , Aarhus University Hospital , Aarhus N DK-8200 , Denmark.

PMID: 26034595 PMCID: PMC4440474 DOI: 10.1093/ckj/sfv027

Abstract

Influenza can cause significant morbidity and mortality in renal transplant recipients especially with a high rate of lower respiratory disease. Annual influenza vaccination is therefore recommended to renal transplant recipients. We report the first three cases of acute kidney injury in renal transplant recipients following influenza vaccination that all led to graft loss. They all had different native diseases and were all vaccinated in the same season of 2009-10. The time span from vaccination to decline of kidney function is shorter than the time to diagnosis since the three patients only had blood tests every 3 months or when symptoms became severe. These reports do not justify a change of current recommendations regarding influenza vaccination in renal transplant recipients, but they support the continued attention and registration of vaccinations to monitor side effects.

Keywords: acute kidney injury; influenza vaccination; kidney graft rejection; renal transplant recipient

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