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Procaccino L, Rehman S, Abdurakhmanov A, et al. Adenocarcinoma arising at ileostomy sites: Two cases and a review of the literature. World J Gastrointest Surg. 2015;7(6):94-7doi: 10.4240/wjgs.v7.i6.94.
Procaccino, L., Rehman, S., Abdurakhmanov, A., McWhorter, P., La Gamma, N., Bhaskaran, M. C., Maurer, J., Grimaldi, G. M., Rilo, H., Nicastro, J., Coppa, G., Molmenti, E. P., & Procaccino, J. (2015). Adenocarcinoma arising at ileostomy sites: Two cases and a review of the literature. World journal of gastrointestinal surgery, 7(6), 94-7. https://doi.org/10.4240/wjgs.v7.i6.94
Procaccino, Lauren, et al. "Adenocarcinoma arising at ileostomy sites: Two cases and a review of the literature." World journal of gastrointestinal surgery vol. 7,6 (2015): 94-7. doi: https://doi.org/10.4240/wjgs.v7.i6.94
Procaccino L, Rehman S, Abdurakhmanov A, McWhorter P, La Gamma N, Bhaskaran MC, Maurer J, Grimaldi GM, Rilo H, Nicastro J, Coppa G, Molmenti EP, Procaccino J. Adenocarcinoma arising at ileostomy sites: Two cases and a review of the literature. World J Gastrointest Surg. 2015 Jun 27;7(6):94-7. doi: 10.4240/wjgs.v7.i6.94. PMID: 26131331; PMCID: PMC4478561.
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World J Gastrointest Surg. 2015 Jun 27;7(6):94-7. doi: 10.4240/wjgs.v7.i6.94.

Adenocarcinoma arising at ileostomy sites: Two cases and a review of the literature.

World journal of gastrointestinal surgery

Lauren Procaccino, Sameer Rehman, Alexander Abdurakhmanov, Peter McWhorter, Nicholas La Gamma, Madhu C Bhaskaran, James Maurer, Gregory M Grimaldi, Horacio Rilo, Jeffrey Nicastro, Gene Coppa, Ernesto P Molmenti, John Procaccino

Affiliations

  1. Lauren Procaccino, Sameer Rehman, Alexander Abdurakhmanov, Peter McWhorter, Nicholas La Gamma, Madhu C Bhaskaran, James Maurer, Gregory M Grimaldi, Horacio Rilo, Jeffrey Nicastro, Gene Coppa, Ernesto P Molmenti, John Procaccino, Department of Surgery, North Shore University Hospital, Manhasset, NY 11030, United States.

PMID: 26131331 PMCID: PMC4478561 DOI: 10.4240/wjgs.v7.i6.94

Abstract

Total colectomy with ileostomy placement is a treatment for patients with inflammatory bowel disease or familial adenomatous polyposis (FAP). A rare and late complication of this treatment is carcinoma arising at the ileostomy site. We describe two such cases: a 78-year-old male 30 years after subtotal colectomy and ileostomy for FAP, and an 85-year-old male 50 years after colectomy and ileostomy for ulcerative colitis. The long latency period between creation of the ileostomies and development of carcinoma suggests a chronic metaplasia due to an irritating/inflammatory causative factor. Surgical excision of the mass and relocation of the stoma is the mainstay of therapy, with possible benefits from adjuvant chemotherapy. Newly developed lesions at stoma sites should be biopsied to rule out the possibility of this rare ileostomy complication.

Keywords: Adenocarcinoma; Carcinoma; Complication of ileostomy; Familial adenomatous polyposis; Ileostomy; Inflammatory bowel disease

References

  1. Gastroenterology. 1988 Jul;95(1):205-8 - PubMed
  2. Ostomy Wound Manage. 2010 Jan 1;56(1):45-7 - PubMed
  3. Dis Colon Rectum. 2008 May;51(5):604-9 - PubMed
  4. Dis Colon Rectum. 1969 Jan-Feb;12(1):45-8 - PubMed
  5. Cancer. 1982 May 15;49(10):2180-4 - PubMed
  6. Lancet. 1952 Jul 19;2(6725):102-4 - PubMed
  7. J Med Case Rep. 2011 Nov 30;5:556 - PubMed
  8. Gut. 1988 Nov;29(11):1607-12 - PubMed
  9. Colorectal Dis. 2005 Nov;7(6):538-44 - PubMed

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