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Frenette A, Morrell J, Bjella K, et al. Do Diametric Measurements Provide Sufficient and Reliable Tumor Assessment? An Evaluation of Diametric, Areametric, and Volumetric Variability of Lung Lesion Measurements on Computerized Tomography Scans. J Oncol. 2015;2015:632943doi: 10.1155/2015/632943.
Frenette, A., Morrell, J., Bjella, K., Fogarty, E., Beal, J., & Chaudhary, V. (2015). Do Diametric Measurements Provide Sufficient and Reliable Tumor Assessment? An Evaluation of Diametric, Areametric, and Volumetric Variability of Lung Lesion Measurements on Computerized Tomography Scans. Journal of oncology, 2015632943. https://doi.org/10.1155/2015/632943
Frenette, Aaron, et al. "Do Diametric Measurements Provide Sufficient and Reliable Tumor Assessment? An Evaluation of Diametric, Areametric, and Volumetric Variability of Lung Lesion Measurements on Computerized Tomography Scans." Journal of oncology vol. 2015 (2015): 632943. doi: https://doi.org/10.1155/2015/632943
Frenette A, Morrell J, Bjella K, Fogarty E, Beal J, Chaudhary V. Do Diametric Measurements Provide Sufficient and Reliable Tumor Assessment? An Evaluation of Diametric, Areametric, and Volumetric Variability of Lung Lesion Measurements on Computerized Tomography Scans. J Oncol. 2015;2015:632943. doi: 10.1155/2015/632943. Epub 2015 May 10. PMID: 26064117; PMCID: PMC4441994.
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J Oncol. 2015;2015:632943. doi: 10.1155/2015/632943. Epub 2015 May 10.

Do Diametric Measurements Provide Sufficient and Reliable Tumor Assessment? An Evaluation of Diametric, Areametric, and Volumetric Variability of Lung Lesion Measurements on Computerized Tomography Scans.

Journal of oncology

Aaron Frenette, Joshua Morrell, Kirk Bjella, Edward Fogarty, James Beal, Vijay Chaudhary

Affiliations

  1. Sanford Health, 300 N. Seventh Street, Bismarck, ND 58501, USA.

PMID: 26064117 PMCID: PMC4441994 DOI: 10.1155/2015/632943

Abstract

Diametric analysis is the standard approach utilized for tumor measurement on medical imaging. However, the availability of newer more sophisticated techniques may prove advantageous. An evaluation of diameter, area, and volume was performed on 64 different lung lesions by three trained users. These calculations were obtained using a free DICOM viewer and standardized measuring procedures. Measurement variability was then studied using relative standard deviation (RSD) and intraclass correlation. Volumetric measurements were shown to be more precise than diametric. With minimal RSD and variance between different users, volumetric analysis was demonstrated as a reliable measurement technique. Additionally, the diameters were used to calculate an estimated area and volume; thereafter the estimated area and volume were compared against the actual measured values. The results in this study showed independence of the estimated and actual values. Estimated area deviated an average of 43.5% from the actual measured, and volume deviated 88.03%. The range of this variance was widely scattered and without trend. These results suggest that diametric measurements cannot be reliably correlated to actual tumor size. Access to appropriate software capable of producing volume measurements has improved drastically and shows great potential in the clinical assessment of tumors. Its applicability merits further consideration.

References

  1. Eur Radiol. 2004 Jan;14 (1):86-92 - PubMed
  2. J Natl Cancer Inst. 2000 Feb 2;92 (3):205-16 - PubMed
  3. Eur Radiol. 2007 Oct;17 (10 ):2561-71 - PubMed
  4. World J Surg. 2011 Feb;35(2):386-92 - PubMed
  5. Radiology. 2000 Oct;217(1):251-6 - PubMed
  6. Radiol Med. 2006 Apr;111(3):365-75 - PubMed
  7. Eur J Orthod. 2007 Feb;29(1):88-94 - PubMed
  8. Acad Radiol. 2004 Dec;11(12 ):1355-60 - PubMed
  9. Anticancer Drugs. 1999 Sep;10(8):693-8 - PubMed
  10. Lung Cancer. 2004 Jan;43(1):63-9 - PubMed
  11. Opt Express. 2010 Apr 12;18(8):8151-9 - PubMed
  12. Eur J Radiol. 2014 Mar;83(3):487-96 - PubMed
  13. Eur J Cancer. 2009 Jan;45(2):228-47 - PubMed
  14. J Clin Oncol. 1997 Dec;15(12):3507-14 - PubMed
  15. Eur Radiol. 2006 Apr;16(4):781-90 - PubMed
  16. Lung Cancer. 2013 Oct;82(1):76-82 - PubMed
  17. J Digit Imaging. 2004 Sep;17(3):205-16 - PubMed

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