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Bo X, Ma L, Fan J, et al. Epicardial fat volume is correlated with coronary lesion and its severity. Int J Clin Exp Med. 2015;8(3):4328-34
Bo, X., Ma, L., Fan, J., Jiang, Z., Zhou, Y., Zhang, L., & Li, W. (2015). Epicardial fat volume is correlated with coronary lesion and its severity. International journal of clinical and experimental medicine, 8(3), 4328-34.
Bo, Xiaohong, et al. "Epicardial fat volume is correlated with coronary lesion and its severity." International journal of clinical and experimental medicine vol. 8,3 (2015): 4328-34.
Bo X, Ma L, Fan J, Jiang Z, Zhou Y, Zhang L, Li W. Epicardial fat volume is correlated with coronary lesion and its severity. Int J Clin Exp Med. 2015 Mar 15;8(3):4328-34. eCollection 2015. PMID: 26064349; PMCID: PMC4443183.
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Int J Clin Exp Med. 2015 Mar 15;8(3):4328-34. eCollection 2015.

Epicardial fat volume is correlated with coronary lesion and its severity.

International journal of clinical and experimental medicine

Xiaohong Bo, Likun Ma, Jili Fan, Zhe Jiang, Yuansong Zhou, Lei Zhang, Wanjun Li

Affiliations

  1. Department of Cardiology, Provincial Hospital Affiliated to Anhui Medical University Hefei 230001, China ; Department of Cardiology, Taihe County People's Hospital Taihe 236600, China.
  2. Department of Cardiology, Provincial Hospital Affiliated to Anhui Medical University Hefei 230001, China.
  3. Department of Cardiology, Taihe County People's Hospital Taihe 236600, China.

PMID: 26064349 PMCID: PMC4443183

Abstract

OBJECTIVE: To evaluate the correlation of epicardial adipose tissue volume (EATV) with the coronary artery lesion and its severity.

METHODS: Inpatients with suspicious stable angina of coronary heart lesion were recruited. For patients with coronary artery lesions in CTA, further coronary angiography (CAG) was performed to evaluate the coronary artery lesion. Gensini scoring system was employed to assess the severity of coronary artery lesions.

RESULTS: Patients were classified as coronary heart disease (CHD) group (n = 160). Results showed the mean EATV was 192.57 ± 30.32 cm(3) in CHD group, which was significantly larger than that in control group (138.56 ± 23.18 cm(3); P < 0.01). The coronary artery stenosis was classified as mild, moderate and severe stenosis according to the extent of coronary artery lesions, and results showed marked difference in the EATV among patients with different severities of coronary artery stenosis (P < 0.005). The Gensini score was positively related to EATV (r = 0.285, P = 0.000). The EATV increased with the increase in the number of affected coronary arteries. Multivariate Logistic regression analysis showed EATV was an independent risk factor of CHD after adjusting other confounding factors (OR = 1.023, P = 0.013).

CONCLUSION: EATV is closely related to the severity of coronary artery lesions: the larger the EATV, the more severe the coronary artery lesions. Moreover, EATV is an independent risk factor of CHD.

Keywords: Volume of epicardial adipose tissue; computer-assisted tomography; coronary arteriography; coronary artery lesion

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