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Neurol Res. 2015 Jun 29; doi: 10.1179/1743132815Y.0000000062. Epub 2015 Jun 29.

Inhibition of neuronal nitric oxide synthase improves microregional O.

Neurological research

Oak Z Chi, Kang H Rah, Sylviana Barsoum, Xia Liu, Harvey R Weiss

PMID: 26119517 DOI: 10.1179/1743132815Y.0000000062

Abstract

Objectives Return of regional cerebral blood flow (rCBF) in focal cerebral ischaemia may not ensure proper distribution of blood flow to meet metabolic demand. This study was performed to determine how inhibition of neuronal nitric oxide synthase (NOS) during ischaemia-reperfusion would affect microregional O

Keywords: Heterogeneity; Ischaemia/reperfusion; Neuronal nitric oxide synthase; Neuroprotection; Regional cerebral blood flow; Venous O2 saturation

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