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Indian J Crit Care Med. 2015 Jun;19(6):333-9. doi: 10.4103/0972-5229.158273.

Invasive candidiasis in non neutropenic critically ill - need for region-specific management guidelines.

Indian journal of critical care medicine : peer-reviewed, official publication of Indian Society of Critical Care Medicine

Armin Ahmed, Afzal Azim, A K Baronia, Rungmei S K Marak, Mohan Gurjar

Affiliations

  1. Department of Critical Care Medicine, SGPGIMS, Lucknow, Uttar Pradesh, India.
  2. Department of Microbiology, SGPGIMS, Lucknow, Uttar Pradesh, India.

PMID: 26195859 PMCID: PMC4478674 DOI: 10.4103/0972-5229.158273

Abstract

Use of antifungal agents has increased over past few decades. A number of risk factors such as immunosuppression, broad spectrum antibiotics, dialysis, pancreatitis, surgery, etc., have been linked with the increased risk of invasive candidiasis. Though there are various guidelines available for the use of antifungal therapy, local/regional epidemiology plays an important role in determining the appropriate choice of agent in situations where the offending organism is not known (i.e. empirical, prophylactic or preemptive therapy). Developing countries like India need to generate their own epidemiological data to facilitate appropriate use of antifungal therapy. In this article, the authors have highlighted the need for region-specific policies/guidelines for treatment of invasive candidiasis. Currently available Indian literature on candidemia epidemiology has also been summarized here.

Keywords: Antifungal prescription; candidemia; critically ill; epidemiology

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