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Abbasi A, Forsberg K, Bischof F. The role of the ubiquitin-editing enzyme A20 in diseases of the central nervous system and other pathological processes. Front Mol Neurosci. 2015;8:21doi: 10.3389/fnmol.2015.00021.
Abbasi, A., Forsberg, K., & Bischof, F. (2015). The role of the ubiquitin-editing enzyme A20 in diseases of the central nervous system and other pathological processes. Frontiers in molecular neuroscience, 821. https://doi.org/10.3389/fnmol.2015.00021
Abbasi, Asghar, et al. "The role of the ubiquitin-editing enzyme A20 in diseases of the central nervous system and other pathological processes." Frontiers in molecular neuroscience vol. 8 (2015): 21. doi: https://doi.org/10.3389/fnmol.2015.00021
Abbasi A, Forsberg K, Bischof F. The role of the ubiquitin-editing enzyme A20 in diseases of the central nervous system and other pathological processes. Front Mol Neurosci. 2015 Jun 15;8:21. doi: 10.3389/fnmol.2015.00021. eCollection 2015. PMID: 26124703; PMCID: PMC4466442.
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Front Mol Neurosci. 2015 Jun 15;8:21. doi: 10.3389/fnmol.2015.00021. eCollection 2015.

The role of the ubiquitin-editing enzyme A20 in diseases of the central nervous system and other pathological processes.

Frontiers in molecular neuroscience

Asghar Abbasi, Kirsi Forsberg, Felix Bischof

Affiliations

  1. Department of Neuroimmunology, Hertie Institute for Clinical Brain Research and Center of Neurology, University Hospital Tübingen Tübingen, Germany.

PMID: 26124703 PMCID: PMC4466442 DOI: 10.3389/fnmol.2015.00021

Abstract

In recent years, the ubiquitin-editing enzyme A20 has been shown to control a large set of molecular pathways involved in the regulation of protective as well as self-directed immune responses. Here, we assess the current and putative roles of A20 in inflammatory, vascular and degenerative diseases of the central nervous system and explore future directions of research.

Keywords: A20; NF-κB; central nervous system; neurodegenerative diseases; neuroinflammation

References

  1. Nat Immunol. 2004 Oct;5(10 ):1052-60 - PubMed
  2. Neurochem Res. 2006 Jan;31(1):21-32 - PubMed
  3. J Neuropathol Exp Neurol. 2007 Oct;66(10):955-64 - PubMed
  4. J Biol Chem. 2009 Mar 27;284(13):8217-21 - PubMed
  5. Cell Mol Life Sci. 2012 Mar;69(6):963-79 - PubMed
  6. J Mol Cell Cardiol. 2014 Jul;72:85-94 - PubMed
  7. Mol Cell. 2008 Jun 20;30(6):678-88 - PubMed
  8. Blood. 2009 Sep 17;114(12 ):2467-75 - PubMed
  9. Science. 2003 Feb 28;299(5611):1355-9 - PubMed
  10. Blood. 2011 Feb 17;117(7):2227-36 - PubMed
  11. Genes Chromosomes Cancer. 2008 Jan;47(1):1-7 - PubMed
  12. Adv Exp Med Biol. 2014;809:33-48 - PubMed
  13. Exp Gerontol. 2014 Jun;54:58-66 - PubMed
  14. QJM. 2014 Jan;107(1):51-5 - PubMed
  15. J Cell Physiol. 2006 Aug;208(2):307-18 - PubMed
  16. Nat Struct Mol Biol. 2010 Aug;17 (8):939-47 - PubMed
  17. Blood. 1998 Oct 15;92 (8):2759-65 - PubMed
  18. PLoS Genet. 2008 Aug 15;4(8):e1000161 - PubMed
  19. Cell Death Differ. 2011 Dec;18(12 ):1845-53 - PubMed
  20. Nature. 2013 Feb 21;494(7437):371-4 - PubMed
  21. EMBO Rep. 2009 Nov;10(11):1272-8 - PubMed
  22. Inflamm Bowel Dis. 2002 May;8(3):201-12 - PubMed
  23. Hum Mol Genet. 2013 May 1;22(9):1826-42 - PubMed
  24. Mult Scler. 2013 Jun;19(7):863-70 - PubMed
  25. EMBO J. 2007 Nov 14;26(22):4634-45 - PubMed
  26. J Clin Oncol. 2006 Jan 10;24(2):274-87 - PubMed
  27. Immunity. 2008 Mar;28(3):381-90 - PubMed
  28. Mol Cell Biol. 1994 Sep;14(9):5661-70 - PubMed
  29. Nat Cell Biol. 2005 Aug;7(8):758-65 - PubMed
  30. PLoS Biol. 2010 Feb 23;8(2):e1000319 - PubMed
  31. Nat Rev Cancer. 2010 May;10 (5):332-41 - PubMed
  32. Expert Opin Ther Targets. 2007 Feb;11(2):123-32 - PubMed
  33. Nature. 2009 Jun 4;459(7247):712-6 - PubMed
  34. Immunity. 2003 Nov;19(5):749-58 - PubMed
  35. Nature. 2004 Aug 5;430(7000):694-9 - PubMed
  36. Biochem J. 2004 Mar 15;378(Pt 3):727-34 - PubMed
  37. Trends Immunol. 2013 Jun;34(6):282-9 - PubMed
  38. Lab Invest. 1997 Sep;77(3):257-67 - PubMed
  39. Free Radic Biol Med. 1998 Jul 1 ;25(1):57-65 - PubMed
  40. Mol Cell. 2013 Mar 7;49(5):908-21 - PubMed
  41. Hum Mol Genet. 2010 Nov 15;19(22):4373-84 - PubMed
  42. Nat Genet. 2009 Feb;41(2):199-204 - PubMed
  43. Science. 1989 Mar 24;243(4898):1576-83 - PubMed
  44. Nat Genet. 2011 Aug 14;43(9):908-12 - PubMed
  45. Sci Signal. 2013 Jun 04;6(278):ra44 - PubMed
  46. Genes Immun. 2011 Apr;12 (3):176-82 - PubMed
  47. Nature. 2007 Feb 22;445(7130):866-73 - PubMed
  48. Trends Immunol. 2014 Jan;35(1):22-31 - PubMed
  49. Expert Opin Ther Targets. 2009 Jul;13(7):733-41 - PubMed
  50. J Immunol. 2013 Jul 15;191(2):535-9 - PubMed
  51. Circ Res. 2013 Jun 7;112(12):1583-91 - PubMed
  52. Mod Pathol. 2012 May;25(5):651-60 - PubMed
  53. Cell Death Differ. 2010 Dec;17 (12 ):1830-41 - PubMed
  54. Antioxid Redox Signal. 1999 Summer;1(2):129-44 - PubMed
  55. BMC Neurosci. 2012 Jul 11;13:45 - PubMed
  56. J Immunol. 2004 Jul 15;173(2):1344-54 - PubMed
  57. Nat Immunol. 2006 Sep;7(9):954-61 - PubMed
  58. Immunity. 2011 Jul 22;35(1):82-96 - PubMed
  59. Blood. 2009 May 14;113(20):4918-21 - PubMed
  60. Mol Cell Biol. 2006 Oct;26(19):7283-98 - PubMed
  61. Cell Death Differ. 2006 May;13(5):852-60 - PubMed
  62. J Neuroimmunol. 2014 Jul 15;272(1-2):99-102 - PubMed
  63. Cell Cycle. 2010 Jul 1;9(13):2481-2 - PubMed
  64. Nat Immunol. 2009 Nov;10(11):1215-21 - PubMed
  65. J Immunol. 1999 Sep 1;163(5):2937-43 - PubMed
  66. J Neurosci. 2014 Apr 23;34(17):5882-94 - PubMed
  67. Leukemia. 2010 Feb;24(2):483-7 - PubMed
  68. J Biol Chem. 2008 Mar 14;283(11):7036-45 - PubMed
  69. J Biol Chem. 1995 May 26;270(21):12343-6 - PubMed
  70. Nat Rev Immunol. 2009 Aug;9(8):556-67 - PubMed
  71. Mol Cell Biol. 2013 Jul;33(14):2797-808 - PubMed
  72. Blood. 2004 Oct 15;104(8):2376-84 - PubMed
  73. Biochem J. 2001 Aug 1;357(Pt 3):617-23 - PubMed
  74. Biochim Biophys Acta. 2014 Jan;1843(1):129-36 - PubMed
  75. J Biol Chem. 2011 Feb 11;286(6):4098-106 - PubMed
  76. Proc Natl Acad Sci U S A. 2007 Nov 20;104(47):18754-9 - PubMed
  77. Eur J Immunol. 1998 Nov;28(11):3594-604 - PubMed
  78. Circulation. 2003 Sep 2;108(9):1113-8 - PubMed
  79. Curr Opin Neurol. 2001 Feb;14(1):89-94 - PubMed
  80. Nature. 2009 Jun 4;459(7247):717-21 - PubMed
  81. Biochim Biophys Acta. 2005 Sep 30;1745(3):287-99 - PubMed
  82. Nat Genet. 2008 Sep;40(9):1062-4 - PubMed
  83. Mol Neurodegener. 2013 Oct 12;8:40 - PubMed
  84. J Clin Invest. 2012 Dec;122(12 ):4698-709 - PubMed
  85. Leuk Lymphoma. 2011 Jan;52(1):108-21 - PubMed
  86. J Immunol. 1996 Feb 1;156(3):1166-73 - PubMed
  87. Cancer Res. 2000 Aug 1;60(15):4085-92 - PubMed
  88. J Biol Chem. 1998 Nov 20;273(47):31262-72 - PubMed
  89. J Immunol. 2009 Jun 15;182(12 ):7718-28 - PubMed
  90. Science. 2000 Sep 29;289(5488):2350-4 - PubMed
  91. Nature. 2002 Jun 20;417(6891):861-6 - PubMed
  92. Neurology. 1999 Aug 11;53(3):457-65 - PubMed
  93. Arch Neurol. 2011 Jul;68(7):879-88 - PubMed
  94. Synapse. 2000 Feb;35(2):151-9 - PubMed
  95. Front Biol (Beijing). 2012 Aug;7(4):null - PubMed
  96. J Virol. 1996 Dec;70(12 ):8653-9 - PubMed
  97. Neurosci Lett. 2013 Jun 28;547:16-20 - PubMed
  98. Cold Spring Harb Perspect Biol. 2010 Mar;2(3):a003350 - PubMed
  99. J Biol Chem. 2006 Jul 7;281(27):18482-8 - PubMed
  100. Nat Genet. 2010 Nov;42(11):985-90 - PubMed
  101. Cell. 2000 Oct 13;103(2):351-61 - PubMed
  102. Ann Rheum Dis. 2004 Nov;63 Suppl 2:ii57-ii61 - PubMed
  103. Dis Model Mech. 2012 Jul;5(4):423-33 - PubMed
  104. Hum Genet. 2010 Dec;128(6):627-33 - PubMed
  105. Cell Death Differ. 2001 Mar;8(3):265-72 - PubMed
  106. Immun Ageing. 2008 Jul 16;5:5 - PubMed
  107. Cancer Res. 2004 Jan 15;64(2):472-81 - PubMed
  108. Lancet Neurol. 2014 Jan;13(1):11-3 - PubMed
  109. Biochem Pharmacol. 2000 Oct 15;60(8):1143-51 - PubMed
  110. Nat Genet. 2013 Nov;45(11):1353-60 - PubMed
  111. Mol Cell Biol. 2002 Sep;22(17 ):6034-45 - PubMed
  112. Oncogene. 1999 Jul 22;18(29):4182-90 - PubMed
  113. Nat Rev Immunol. 2012 Nov;12 (11):774-85 - PubMed
  114. Sci Signal. 2010 May 25;3(123):ra42 - PubMed
  115. Trends Biochem Sci. 2000 Feb;25(2):50-2 - PubMed
  116. J Biol Chem. 2012 Jul 13;287(29):24573-84 - PubMed
  117. Glia. 2014 Mar;62(3):452-67 - PubMed
  118. Cancer Res. 2001 Mar 15;61(6):2656-64 - PubMed
  119. J Exp Med. 2009 May 11;206(5):977-80 - PubMed
  120. Nat Genet. 2009 Jul;41(7):776-82 - PubMed
  121. Leukemia. 2011 Sep;25(9):1494-501 - PubMed
  122. J Neuropathol Exp Neurol. 2014 Jul;73(7):714-28 - PubMed
  123. J Exp Med. 2009 May 11;206(5):981-9 - PubMed
  124. PLoS One. 2014 Jan 31;9(1):e87425 - PubMed
  125. Nat Immunol. 2008 Mar;9(3):263-71 - PubMed
  126. Arthritis Rheum. 2013 Apr;65(4):928-38 - PubMed
  127. J Neurochem. 2009 Jan;108(2):475-85 - PubMed
  128. Brain. 2012 Sep;135(Pt 9):2750-65 - PubMed
  129. J Immunol. 2013 Mar 15;190(6):2896-903 - PubMed
  130. Trends Immunol. 2009 Aug;30(8):383-91 - PubMed
  131. J Neurosurg. 2005 Nov;103(5):873-81 - PubMed
  132. N Engl J Med. 2009 Jul 30;361(5):496-509 - PubMed
  133. Nat Neurosci. 2003 Oct;6(10):1072-8 - PubMed
  134. Acta Neuropathol. 2013 Sep 29;126(5):711-724 - PubMed
  135. Nat Genet. 2009 Nov;41(11):1228-33 - PubMed
  136. Arthritis Rheum. 2010 Feb;62(2):574-9 - PubMed
  137. Neurosci Lett. 2012 Oct 24;528(2):174-9 - PubMed
  138. Autophagy. 2011 Mar;7(3):341-5 - PubMed
  139. Immunity. 2013 Nov 14;39(5):899-911 - PubMed
  140. J Biol Chem. 2007 Mar 23;282(12):8724-33 - PubMed
  141. J Biol Chem. 1992 Jun 25;267(18):12424-7 - PubMed
  142. J Neurosci. 2013 Oct 16;33(42):16490-501 - PubMed
  143. J Biol Chem. 2003 Sep 26;278(39):37297-305 - PubMed
  144. J Invest Dermatol. 2012 Mar;132(3 Pt 1):593-600 - PubMed
  145. Genes Dev. 2007 Dec 15;21(24):3244-57 - PubMed
  146. Lab Invest. 2009 Jul;89(7):742-59 - PubMed
  147. Histol Histopathol. 2006 Jan;21(1):69-80 - PubMed
  148. Nature. 2006 May 4;441(7089):106-10 - PubMed
  149. Int J Biochem Cell Biol. 2008;40(2):176-80 - PubMed

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