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Ogawa R, Watanabe H, Yazaki K, et al. Lung cancer with spontaneous regression of primary and metastatic sites: A case report. Oncol Lett. 2015;10(1):550-552doi: 10.3892/ol.2015.3243.
Ogawa, R., Watanabe, H., Yazaki, K., Fujita, K., Tsunoda, Y., Nakazawa, K., Homma, S., Kagohashi, K., Satoh, H., & Hizawa, N. (2015). Lung cancer with spontaneous regression of primary and metastatic sites: A case report. Oncology letters, 10(1), 550-552. https://doi.org/10.3892/ol.2015.3243
Ogawa, Ryoko, et al. "Lung cancer with spontaneous regression of primary and metastatic sites: A case report." Oncology letters vol. 10,1 (2015): 550-552. doi: https://doi.org/10.3892/ol.2015.3243
Ogawa R, Watanabe H, Yazaki K, Fujita K, Tsunoda Y, Nakazawa K, Homma S, Kagohashi K, Satoh H, Hizawa N. Lung cancer with spontaneous regression of primary and metastatic sites: A case report. Oncol Lett. 2015 Jul;10(1):550-552. doi: 10.3892/ol.2015.3243. Epub 2015 May 20. PMID: 26171067; PMCID: PMC4487128.
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Oncol Lett. 2015 Jul;10(1):550-552. doi: 10.3892/ol.2015.3243. Epub 2015 May 20.

Lung cancer with spontaneous regression of primary and metastatic sites: A case report.

Oncology letters

Ryoko Ogawa, Hiroko Watanabe, Kai Yazaki, Kazutaka Fujita, Yoshiya Tsunoda, Kensuke Nakazawa, Shinsuke Homma, Katsunori Kagohashi, Hiroaki Satoh, Nobuyuki Hizawa

Affiliations

  1. Division of Respiratory Medicine, Faculty of Medicine, University of Tsukuba, Mito, Ibaraki 310-0015, Japan.
  2. Division of Respiratory Medicine, Mito Medical Center, University of Tsukuba, Mito, Ibaraki 310-0015, Japan.

PMID: 26171067 PMCID: PMC4487128 DOI: 10.3892/ol.2015.3243

Abstract

Partial or complete spontaneous cancer regression is a rare phenomenon, particularly in patients with lung cancer. This is the case report of a patient with lung cancer who exhibited spontaneous regression of the primary as well as metastatic lesions, without receiving any treatment. Spontaneous regression commenced within a week of obtaining pathological specimens by transbronchial and percutaneous biopsies from the primary lesion and metastatic lymph nodes of the left side of the neck. The reason for this phenomenon is unknown; however, we hypothesized that there may be an immunological association between the stimulus of the biopsies and the spontaneous regression. This patient should be closely followed up to monitor the clinical course of this unusual case.

Keywords: lung cancer; metastasis; primary tumor; spontaneous regression

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