Display options
Share it on

Rev Bras Ortop. 2015 Mar 27;50(2):239-42. doi: 10.1016/j.rboe.2015.03.004. eCollection 2015.

Gorham's disease: clinical case.

Revista brasileira de ortopedia

Pedro Sá, Pedro Marques, Carolina Oliveira, André Sá Rodrigues, Nelson Amorim, Rui Pinto

Affiliations

  1. Unidade Local de Saúde Alto Minho, Viana do Castelo, Portugal.
  2. Centro Hospitalar São João, Porto, Portugal.

PMID: 26229923 PMCID: PMC4519563 DOI: 10.1016/j.rboe.2015.03.004

Abstract

Gorham's disease, also known as idiopathic massive osteolysis, is a rare pathological condition characterized by vascular proliferation that results in destruction and reabsorption of the bone matrix, of unknown etiology. It was first described by Jackson in 1838, but it was Gorham and Stout, in 1955, who defined this disease as a specific entity. It has variable clinical presentation and generally has progressive behavior. Controversy continues regarding the treatment and there is no standard treatment. This pathological condition generally presents a favorable prognosis. Here, a case of Gorham's disease with involvement of the left hip is presented, in a male patient without relevant antecedents.

Keywords: Essential osteolysis/diagnosis; Essential osteolysis/pathology; Rare diseases/etiology

References

  1. J Bone Joint Surg Br. 1999 May;81(3):501-6 - PubMed
  2. Radiology. 1964 Apr;82:637-44 - PubMed
  3. Chest. 1981 Feb;79(2):242-4 - PubMed
  4. Rofo. 1998 Jan;168(1):68-76 - PubMed
  5. Lancet. 1997 Dec 20-27;350(9094):1822-3 - PubMed
  6. Chest. 1994 Jan;105(1):208-13 - PubMed
  7. Int Orthop. 1997;21(5):303-7 - PubMed
  8. Int J Radiat Oncol Biol Phys. 1993 Jun 15;26(3):491-7 - PubMed
  9. J Bone Joint Surg Br. 1970 Aug;52(3):452-9 - PubMed
  10. J Bone Miner Res. 2005 Feb;20(2):350-3 - PubMed
  11. JAMA. 1984 Sep 21;252(11):1449-51 - PubMed
  12. Clin Orthop Relat Res. 1998 Feb;(347):268-71, 287-90 - PubMed
  13. Skeletal Radiol. 1997 Nov;26(11):659-63 - PubMed
  14. Orthopedics. 2008 Mar;31(3):278 - PubMed
  15. J Bone Joint Surg Am. 1955 Oct;37-A(5):985-1004 - PubMed
  16. Skeletal Radiol. 2002 Dec;31(12):724-9 - PubMed
  17. J Pathol. 2001 Dec;195(5):624-30 - PubMed
  18. Bone. 1990;11(3):205-10 - PubMed
  19. J Clin Endocrinol Metab. 1996 May;81(5):1893-7 - PubMed
  20. Int Orthop. 1990;14 (4):361-6 - PubMed
  21. J Bone Joint Surg Br. 1985 Jan;67(1):88-93 - PubMed

Publication Types