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Geburtshilfe Frauenheilkd. 2015 Jul;75(7):683-691. doi: 10.1055/s-0035-1546270.

The Right Treatment for the Right Patient - Personalised Treatment of Breast Cancer.

Geburtshilfe und Frauenheilkunde

A Scharl, T Kühn, T Papathemelis, A Salterberg

Affiliations

  1. Frauenklinik, Klinikum St. Marien Amberg, Amberg.
  2. Frauenklinik, Klinikum Esslingen, Esslingen.
  3. Department of Gynaecology and Obstetrics, Sana Clinics, Cham.

PMID: 26257405 PMCID: PMC4520989 DOI: 10.1055/s-0035-1546270

Abstract

The probability of healing breast cancer has been greatly improved in recent decades through the introduction and optimisation of multi-modal therapies and interdisciplinary treatments. Today, in addition to surgery or radiation, most patients receive a systemic treatment. To prevent excessive treatment, patients whose prognosis is so good that certain adjuvant therapies can be foregone or reduced must be identified. A lack of compliance with therapy, especially in the endocrine therapies stretching over years, is a further problem. As only treatments that are also carried out can improve chances of survival, efforts to improve compliance must be intensified. Studies show that lifestyle changes influence the efficiency of medication on the one hand, and on the other hand can also by themselves achieve a relevant improvement of the prognosis. Therefore, it is time not only to treat the tumour, but to also focus on the patient as a whole in therapeutic interventions.

Keywords: breast cancer; compliance; excessive treatment; lifestyle changes; over-diagnosis

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