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ACG Case Rep J. 2015 Jul 09;2(4):250-1. doi: 10.14309/crj.2015.75. eCollection 2015 Jul.

Hemolysis in Acute Alcoholic Hepatitis: Zieve's Syndrome.

ACG case reports journal

Sandhya Shukla, Michael Sitrin

Affiliations

  1. Department of Gastroenterology, University of Buffalo, Buffalo, NY.
  2. Department of Hepatology and Nutrition, University of Buffalo, Buffalo, NY.

PMID: 26203455 PMCID: PMC4508957 DOI: 10.14309/crj.2015.75

Abstract

A 45-year-old man presented with acute alcoholic hepatitis, jaundice, and anemia on admission. There was no history of bleeding or any evidence of gastrointestinal blood loss. Lab studies revealed hemolysis as the cause of anemia. The patient was diagnosed with Zieve's syndrome and managed with supportive measures. He recovered well and was discharged to a detoxification unit in a stable condition. Zieve's syndrome has been described in literature, mostly in non-English language case studies, but is largely under-recognized and under-reported. Diagnosis should be made quickly to avoid unnecessary invasive diagnostic interventions.

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