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Kwon H, Jiang W, Kool ET. Pattern-Based Detection of Anion Pollutants in Water with DNA Polyfluorophores. Chem Sci. 2015;6(4):2575-2583doi: 10.1039/C4SC03992K.
Kwon, H., Jiang, W., & Kool, E. T. (2015). Pattern-Based Detection of Anion Pollutants in Water with DNA Polyfluorophores. Chemical science, 6(4), 2575-2583. https://doi.org/10.1039/C4SC03992K
Kwon, Hyukin, et al. "Pattern-Based Detection of Anion Pollutants in Water with DNA Polyfluorophores." Chemical science vol. 6,4 (2015): 2575-2583. doi: https://doi.org/10.1039/C4SC03992K
Kwon H, Jiang W, Kool ET. Pattern-Based Detection of Anion Pollutants in Water with DNA Polyfluorophores. Chem Sci. 2015 Apr 01;6(4):2575-2583. doi: 10.1039/C4SC03992K. PMID: 26146537; PMCID: PMC4486361.
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Chem Sci. 2015 Apr 01;6(4):2575-2583. doi: 10.1039/C4SC03992K.

Pattern-Based Detection of Anion Pollutants in Water with DNA Polyfluorophores.

Chemical science

Hyukin Kwon, Wei Jiang, Eric T Kool

Affiliations

  1. Department of Chemistry, Stanford University, Stanford, California 94305-5080, United States. ; Tel: +650 724 4741.

PMID: 26146537 PMCID: PMC4486361 DOI: 10.1039/C4SC03992K

Abstract

Many existing irrigation, industrial and chemical storage sites are currently introducing hazardous anions into groundwater, making the monitoring of such sites a high priority. Detecting and quantifying anions in water samples typically requires complex instrumentation, adding cost and delaying analysis. Here we address these challenges by development of an optical molecular method to detect and discriminate a broad range of anionic contaminants with DNA-based fluorescent sensors. A library of 1296 tetrameric-length oligodeoxyfluorosides (ODFs) composed of metal ligand and fluorescence modulating monomers was constructed with a DNA synthesizer on PEG-polystyrene microbeads. These oligomers on beads were incubated with Y

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