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J Ophthalmic Inflamm Infect. 2015 Dec;5(1):55. doi: 10.1186/s12348-015-0055-y. Epub 2015 Aug 04.

Retinochoroidal toxoplasmosis in a patient with cerebral post-transplant lymphoproliferative disease of Hodgkin's type: a diagnostic challenge.

Journal of ophthalmic inflammation and infection

Ruchi Mittal, Gabrielle Thumann, George Souteyrand, David Kuerten, Sarah E Coupland

Affiliations

  1. Dalmia Ophthalmic Pathology Services, L.V. Prasad Eye Institute, Bhubaneswar, India, [email protected].

PMID: 26239296 PMCID: PMC4523567 DOI: 10.1186/s12348-015-0055-y

Abstract

Toxoplasmosis is a relatively rare complication in renal transplant patients and can pose diagnostic challenges, especially when it manifests as an ocular inflammation. Authors hereby report an unusual case of a 57-year-old male who developed retinochoroidal toxoplasmosis after 15 years of renal transplant, the diagnoses of which were challenging as the patient was also a known case of cerebral post-transplant lymphoproliferative disease (PTLD) of Hodgkin's type, which misled the ophthalmologists towards a clinical diagnosis of ocular PTLD. Histopathology examination of the enucleated eye revealed numerous toxoplasmosis cysts within the retina and choroid. No ocular PTLD was observed.

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