Display options
Cite
Nakaji S, Hirata N, Fujii H, et al. A case of focal autoimmune pancreatitis (AIP) mimicking an intraductal papillary mucinous neoplasm (IPMN). Clin J Gastroenterol. 2013;6(4):329-33doi: 10.1007/s12328-013-0392-z.
Nakaji, S., Hirata, N., Fujii, H., Iwaki, K., Shiratori, T., Kobayashi, M., Wakasugi, S., Ishii, E., Takeyama, H., & Hoshi, K. (2013). A case of focal autoimmune pancreatitis (AIP) mimicking an intraductal papillary mucinous neoplasm (IPMN). Clinical journal of gastroenterology, 6(4), 329-33. https://doi.org/10.1007/s12328-013-0392-z
Nakaji, So, et al. "A case of focal autoimmune pancreatitis (AIP) mimicking an intraductal papillary mucinous neoplasm (IPMN)." Clinical journal of gastroenterology vol. 6,4 (2013): 329-33. doi: https://doi.org/10.1007/s12328-013-0392-z
Nakaji S, Hirata N, Fujii H, Iwaki K, Shiratori T, Kobayashi M, Wakasugi S, Ishii E, Takeyama H, Hoshi K. A case of focal autoimmune pancreatitis (AIP) mimicking an intraductal papillary mucinous neoplasm (IPMN). Clin J Gastroenterol. 2013 Aug;6(4):329-33. doi: 10.1007/s12328-013-0392-z. Epub 2013 Jun 01. PMID: 26181739.
Copy Download .nbib Format: NLM
Share it on

Clin J Gastroenterol. 2013 Aug;6(4):329-33. doi: 10.1007/s12328-013-0392-z. Epub 2013 Jun 01.

A case of focal autoimmune pancreatitis (AIP) mimicking an intraductal papillary mucinous neoplasm (IPMN).

Clinical journal of gastroenterology

So Nakaji, Nobuto Hirata, Hiroyuki Fujii, Kosuke Iwaki, Toshiyasu Shiratori, Masayoshi Kobayashi, Satoshi Wakasugi, Eiji Ishii, Hiroyuki Takeyama, Kazuei Hoshi

Affiliations

  1. Department of Gastroenterology, Kameda Medical Center, 929 Higashi-cho, Kamogawa, Chiba, Japan. [email protected].
  2. Department of Gastroenterology, Kameda Medical Center, 929 Higashi-cho, Kamogawa, Chiba, Japan.
  3. Department of Anatomic Pathology, Kameda Medical Center, Kamogawa, Japan.

PMID: 26181739 DOI: 10.1007/s12328-013-0392-z

Abstract

The present case involved a 76-year-old man with a cystic mass in the head of his pancreas. The cystic lesion, which measured 17.7 × 9.8 mm, was first detected by ultrasonography (US) at the age of 72 years. Follow-up endoscopic ultrasonography (EUS) performed at 4 years after the lesion had first been detected revealed a mural nodule measuring 14.0 × 8.4 mm in the cyst. Endoscopic retrograde pancreatography (ERP) imaging revealed that the main pancreatic duct was in communication with the cyst and that there was no irregular narrowing of the main pancreatic duct. On the basis of these results, the patient was diagnosed with an intraductal papillary mucinous neoplasm (IPMN), and stomach-preserving pancreaticoduodenectomy was performed. A histopathological examination revealed that the interior of the cystic part of the lesion was lined by a pancreatic ductal epithelium. A pathological examination of the nodular lesion detected storiform fibrosis, severe lymphoplasmacytic infiltration, and hyperplasia in the pancreatic duct epithelium together with a small amount of mucus. On immunohistological staining, the infiltrating lymphoplasmacytes were found to be positive for IgG4. Accordingly, the patient was diagnosed with focal autoimmune pancreatitis (AIP). In conclusion, we reported a case of focal AIP mimicking IPMN. This case showed neither enlargement of the pancreas nor irregular narrowing of the main pancreatic duct.

Keywords: Autoimmune pancreatitis; Intraductal papillary mucinous neoplasm; Pancreatic cyst

References

  1. Clin Gastroenterol Hepatol. 2008 Sep;6(9):e33-4 - PubMed
  2. Gastrointest Endosc. 2007 Jan;65(1):99-108 - PubMed
  3. World J Gastroenterol. 2006 Sep 28;12(36):5904-6 - PubMed
  4. Clin Gastroenterol Hepatol. 2006 Aug;4(8):1010-6; quiz 934 - PubMed
  5. Am J Dig Dis. 1961 Jul;6:688-98 - PubMed
  6. Pancreas. 2013 Apr;42(3):552-4 - PubMed
  7. J Gastroenterol. 2005 Jul;40(7):761-6 - PubMed
  8. Intern Med. 2008;47(7):603-8 - PubMed
  9. J Gastroenterol. 2004 Oct;39(10 ):1005-10 - PubMed
  10. Pancreas. 2007 Apr;34(3):279-86 - PubMed
  11. Gut Liver. 2012 Jan;6(1):132-5 - PubMed

Publication Types