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Lee SH, Kim JH, Jeong MH, et al. Clinical Characteristics and Outcomes of Acute ST-Segment Elevation Myocardial Infarction in Younger Korean Adults. Korean Circ J. 2015;45(4):275-84doi: 10.4070/kcj.2015.45.4.275.
Lee, S. H., Kim, J. H., Jeong, M. H., Park, H., Jeong, Y. A., Ahn, Y., Kim, J. H., Chae, S. C., Kim, Y. J., Hur, S. H., Seong, I. W., Hong, T. J., Choi, D., Cho, M. C., Kim, C. J., Seung, K. B., Chung, W. S., Jang, Y. S., Cho, J. G., Park, J. C., Park, S. J. (2015). Clinical Characteristics and Outcomes of Acute ST-Segment Elevation Myocardial Infarction in Younger Korean Adults. Korean circulation journal, 45(4), 275-84. https://doi.org/10.4070/kcj.2015.45.4.275
Lee, Seung Hun, et al. "Clinical Characteristics and Outcomes of Acute ST-Segment Elevation Myocardial Infarction in Younger Korean Adults." Korean circulation journal vol. 45,4 (2015): 275-84. doi: https://doi.org/10.4070/kcj.2015.45.4.275
Lee SH, Kim JH, Jeong MH, Park H, Jeong YA, Ahn Y, Kim JH, Chae SC, Kim YJ, Hur SH, Seong IW, Hong TJ, Choi D, Cho MC, Kim CJ, Seung KB, Chung WS, Jang YS, Cho JG, Park JC, Park SJ. Clinical Characteristics and Outcomes of Acute ST-Segment Elevation Myocardial Infarction in Younger Korean Adults. Korean Circ J. 2015 Jul;45(4):275-84. doi: 10.4070/kcj.2015.45.4.275. Epub 2015 Jun 24. PMID: 26240581; PMCID: PMC4521105.
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Korean Circ J. 2015 Jul;45(4):275-84. doi: 10.4070/kcj.2015.45.4.275. Epub 2015 Jun 24.

Clinical Characteristics and Outcomes of Acute ST-Segment Elevation Myocardial Infarction in Younger Korean Adults.

Korean circulation journal

Seung Hun Lee, Ju Han Kim, Myung Ho Jeong, Hyukjin Park, Yun Ah Jeong, Youngkeun Ahn, Jong Hyun Kim, Shung Chull Chae, Young Jo Kim, Seung Ho Hur, In Whan Seong, Taek Jong Hong, Donghoon Choi, Myeong Chan Cho, Chong Jin Kim, Ki Bae Seung, Wook Sung Chung, Yang Soo Jang, Jeong Gwan Cho, Jong Chun Park, Seung Jung Park,

Affiliations

  1. The Heart Center of Chonnam National University Hospital, Gwangju, Korea.
  2. The Cardiovascular Center, Hanseo Hospital, Busan, Korea.
  3. Department of Internal Medicine, Kyungpook National University Hospital, Daegu, Korea.
  4. Department of Internal Medicine, Yeungnam University Hospital, Daegu, Korea.
  5. Department of Internal Medicine, Keimyung University Dongsan Medical Center, Daegu, Korea.
  6. Department of Internal Medicine, Chungnam National University Hospital, Daejeon, Korea.
  7. Department of Internal Medicine, Pusan National University Hospital, Busan, Korea.
  8. Department of Internal Medicine, Yonsei University Severans Hospital, Seoul, Korea.
  9. Department of Internal Medicine, Chungbuk National University Hospital, Cheongju, Korea.
  10. Department of Internal Medicine, Kyunghee University College of Medicine, Seoul, Korea.
  11. Department of Internal Medicine, The Catholic University of Korea Hospital, Seoul, Korea.
  12. Department of Internal Medicine, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea.

PMID: 26240581 PMCID: PMC4521105 DOI: 10.4070/kcj.2015.45.4.275

Abstract

BACKGROUND AND OBJECTIVES: This study aims to investigate the clinical features, angiographic findings, and outcomes of younger Korean ST-segment elevation myocardial infarction (STEMI) patients.

SUBJECTS AND METHODS: We analyzed major adverse cardiac events (MACE) in the Korea Acute Myocardial Infarction Registry from November 2005 to October 2010. The registered patients were divided into two groups; young age group (<65 years) and old age group (≥65 years).

RESULTS: The young age group included 5281 patients (age, 53±7.8 years), and the old age group included 4896 patients (age, 74.3±6.5 years). Male gender, smoking, family history, dyslipidemia, and metabolic syndrome were more frequently observed in the young age group than in the old age group (89.5% vs. 59.3%, p<0.001; 77.3% vs. 47.2%, p<0.001; 11% vs. 4.6%, p<0.001; 11.2% vs. 7.7%, p<0.001; 67.6% vs. 62.9%, p<0.001). Most of the young Korean adults with STEMI complained of typical chest pain (89.8%), and they had a shorter symptom-to-door time (12±53.2 hours vs. 17.3±132 hours, p=0.010). The young age group showed a favorable prognosis, which was represented by the MACE, compared with the old age group at one month (1.8% vs. 2.8%, p=0.028), six months (6.8% vs. 8.2%, p<0.001), and twelve months (10.1% vs. 11.9%, p=0.025). However, there was no significant difference in the adjusted MACE rate at one month {hazard ratio (HR) 0.95, 95% confidence interval (CI) 0.60-1.51, p=0.828} and twelve months (HR 0.86, 95% CI 0.68-1.10, p=0.233).

CONCLUSION: Younger Korean adults with STEMI have clinical outcomes similar to old aged patients, and therefore, they should be treated intensively like the elderly patients.

Keywords: Myocardial infarction; Prognosis; Young adult

References

  1. Lancet. 2003 Jan 4;361(9351):13-20 - PubMed
  2. Heart. 2004 Jan;90(1):99-106 - PubMed
  3. Circulation. 1981 Oct;64(4):744-53 - PubMed
  4. Circ J. 2008 Mar;72(3):392-8 - PubMed
  5. Circulation. 1999 Mar 23;99(11):1411-5 - PubMed
  6. N Engl J Med. 1999 Aug 26;341(9):625-34 - PubMed
  7. Cardiology. 2007;107(4):217-25 - PubMed
  8. N Engl J Med. 1985 Apr 4;312(14 ):932-6 - PubMed
  9. Circulation. 2004 Jan 27;109(3):433-8 - PubMed
  10. Circulation. 2006 Feb 14;113(6):898-918 - PubMed
  11. Eur Heart J. 1995 Mar;16(3):313-6 - PubMed
  12. Ann Intern Med. 2009 May 5;150(9):604-12 - PubMed
  13. J Korean Med Sci. 2013 Jan;28(1):16-24 - PubMed
  14. J Am Coll Cardiol. 1995 Sep;26(3):654-61 - PubMed
  15. J Am Coll Cardiol. 2002 Oct 16;40(8):1389-94 - PubMed
  16. World Rev Nutr Diet. 2005;94:1-12 - PubMed
  17. JAMA. 1999 Dec 8;282(22):2149-55 - PubMed
  18. J Cardiovasc Dis Res. 2013 Jun;4(2):107-11 - PubMed
  19. Circulation. 2008 Jan 29;117(4):e25-146 - PubMed
  20. Endocrinol Metab Clin North Am. 2003 Dec;32(4):855-67 - PubMed
  21. JAMA. 2005 Jun 15;293(23 ):2865-72 - PubMed
  22. Am J Med. 1999 Sep;107(3):254-61 - PubMed
  23. Int Heart J. 2013;54(3):123-8 - PubMed
  24. JAMA. 2003 Jul 2;290(1):86-97 - PubMed
  25. Lancet. 1992 May 9;339(8802):1128-30 - PubMed

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