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Bhandari B, Kumar L, Datta A, et al. Effect of Sub Maximal Dynamic and Static Exercises on QTc interval in Healthy Young Men. J Clin Diagn Res. 2015;9(6):CC01-4doi: 10.7860/JCDR/2015/12048.6006.
Bhandari, B., Kumar, L., Datta, A., & Sircar, S. (2015). Effect of Sub Maximal Dynamic and Static Exercises on QTc interval in Healthy Young Men. Journal of clinical and diagnostic research : JCDR, 9(6), CC01-4. https://doi.org/10.7860/JCDR/2015/12048.6006
Bhandari, Bharti, et al. "Effect of Sub Maximal Dynamic and Static Exercises on QTc interval in Healthy Young Men." Journal of clinical and diagnostic research : JCDR vol. 9,6 (2015): CC01-4. doi: https://doi.org/10.7860/JCDR/2015/12048.6006
Bhandari B, Kumar L, Datta A, Sircar S. Effect of Sub Maximal Dynamic and Static Exercises on QTc interval in Healthy Young Men. J Clin Diagn Res. 2015 Jun;9(6):CC01-4. doi: 10.7860/JCDR/2015/12048.6006. Epub 2015 Jun 01. PMID: 26266113; PMCID: PMC4525502.
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J Clin Diagn Res. 2015 Jun;9(6):CC01-4. doi: 10.7860/JCDR/2015/12048.6006. Epub 2015 Jun 01.

Effect of Sub Maximal Dynamic and Static Exercises on QTc interval in Healthy Young Men.

Journal of clinical and diagnostic research : JCDR

Bharti Bhandari, Lokesh Kumar, Anjum Datta, Sabyasachi Sircar

Affiliations

  1. Assistant Professor, Department of Physiology, All India Institute of Medical Sciences , Jodhpur, India .
  2. Undergraduate Student, Department of Physiology, All India Institute of Medical Sciences , Jodhpur, India .
  3. Junior Resident, Department of Physiology, All India Institute of Medical Sciences , Jodhpur, India .
  4. Professor and Head, Department of Physiology, All India Institute of Medical Sciences , Jodhpur, India .

PMID: 26266113 PMCID: PMC4525502 DOI: 10.7860/JCDR/2015/12048.6006

Abstract

INTRODUCTION: The QTc interval depends largely on cardiac repolarization since the duration of cardiac depolarization is fairly constant in the normal heart. QTc at rest as well as during exercise has many clinical implications. In this study, we have compared the relative effects of dynamic and static exercise on QTc.

AIM: To measure QTc interval in young men at rest and also assess how it is further modulated by submaximal dynamic and static exercises.

MATERIALS AND METHODS: This observational study was conducted in the Department of Physiology on 30 non-obese young men randomly selected from the students of our institute after obtaining the consent and institutional ethical clearance. Continuous blood pressure monitoring and ECG recording was done in the subjects. Baseline (pre-exercise), post submaximal dynamic (Harvard's step test) and post submaximal static exercise (hand-grip exercise) recordings of ABP and ECG were taken for analysis. The measured QT interval was corrected for heart rate using the formula of Bazett et al., {QTc=QT/RR(1/2)}.Statistical analysis was done using Graph pad Prism 5 software (California, USA). The baseline and post-exercise data were compared using paired t-test. A p<0.05 was taken to be statistical significant.

RESULTS: There were statistically significant increases in HR, SBP, DBP and QTc interval after dynamic exercise in comparison to the baseline values (p<0.05). Significant increase in HR (p<0.05) with no significant change in QTc and other cardiovascular parameters were recorded following static exercise (p>0.05).

CONCLUSION: Significant increase in QTc interval was observed after dynamic exercise, however, no change in QTc was observed following static exercise, and hence we conclude that static exercises may not be useful in assessing the cardiovascular status of an individual or in predicting cardiovascular events.

Keywords: Cardiac repolarization; Electrocardiography; Hand grip test; Harvard’s step test

References

  1. Int J Cardiol. 2003 Feb;87(2-3):217-22 - PubMed
  2. J Pak Med Assoc. 2012 Mar;62(3):273-5 - PubMed
  3. Arch Intern Med. 2004 May 10;164(9):943-8 - PubMed
  4. J Am Coll Cardiol. 1996 Nov 15;28(6):1547-55 - PubMed
  5. Circulation. 2003 Oct 21;108(16):1985-9 - PubMed
  6. J Pediatr. 2002 Jul;141(1):59-63 - PubMed
  7. Hypertension. 2005 Jan;45(1):142-61 - PubMed
  8. JAMA. 2001 Mar 14;285(10):1322-6 - PubMed
  9. Arq Bras Endocrinol Metabol. 2007 Oct;51(7):1153-9 - PubMed
  10. Rev Bras Fisioter. 2010 Sep-Oct;14(5):383-9 - PubMed
  11. Kardiologiia. 2012;52(9):15-21 - PubMed
  12. Diabet Med. 2001 Mar;18(3):199-205 - PubMed
  13. J Clin Diagn Res. 2014 Aug;8(8):BC01-4 - PubMed
  14. Diabetes Care. 2014 May;37(5):1454-61 - PubMed
  15. Geriatr Gerontol Int. 2015 Jul;15(7):895-901 - PubMed
  16. J Electrocardiol. 1995;28 Suppl:206-10 - PubMed
  17. J Am Coll Cardiol. 2004 Feb 18;43(4):565-71 - PubMed
  18. Scand J Clin Lab Invest. 2000 Jul;60(4):323-32 - PubMed
  19. Phys Ther. 2000 Aug;80(8):782-807 - PubMed
  20. Eur J Appl Physiol. 2011 Mar;111(3):557-65 - PubMed
  21. J Electrocardiol. 2004;37 Suppl:81-90 - PubMed
  22. Hypertens Res. 2010 Sep;33(9):916-21 - PubMed
  23. Eur J Epidemiol. 2010 Mar;25(3):195-202 - PubMed

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