J Clin Diagn Res. 2015 Jun;9(6):ZC35-8. doi: 10.7860/JCDR/2015/12292.6091. Epub 2015 Jun 01.
Influence of Vitamin D & Calcium Supplementation in the Management of Periodontitis.
Journal of clinical and diagnostic research : JCDR
Jayachandran Perayil, Keerthy S Menon, Seema Kurup, Anju Elizebath Thomas, Angel Fenol, Rajesh Vyloppillil, Anuradha Bhaskar, Sai Megha
Affiliations
Affiliations
- Professor and HOD, Department of Periodontics, Amrita School of Dentistry , Ponekkara, Kochi, India .
- Post Graduate Trainee, Department of Periodontics, Amrita School of Dentistry , Ponekkara, Kochi, India .
- Professor and HOD, Department of Oral Medicine and Radiology, Amrita School of Dentistry , Ponekkara, Kochi, India .
- Post Graduate Trainee, Department of Oral Medicine and Radiology, Amrita School of Dentistry , Ponekkara, Kochi, India .
- Professor, Department of Periodontics, Amrita School of Dentistry , Ponekkara, Kochi, India .
- Reader, Department of Periodontics, Amrita School of Dentistry , Ponekkara, Kochi, India .
- Assistant Professor, Department of Periodontics, Amrita School of Dentistry , Ponekkara, Kochi, India .
PMID: 26266214
PMCID: PMC4525604 DOI: 10.7860/JCDR/2015/12292.6091
Abstract
INTRODUCTION: It has long been recognized that vitamin D is a hormone and were many studies reporting that patients in periodontal maintenance programs taking vitamin D and calcium supplementation had a trend for better periodontal health compared to patients not taking supplementation.
AIM: To evaluate the effect of vitamin D and calcium supplementation in reducing gingival inflammation, using clinical parameters like gingival index (GI), oral hygiene index-simplified (OHIS), probing pocket depth (PPD), clinical attachment level (CAL) and bone density (BD). Also, to assess whether calcium and vitamin D oral supplementation influences alveolar Bone Density (BD).
DESIGN AND SETTINGS: A nonrandomised clinical trial done in Amrita School of dentistry, Kochi, India.
MATERIALS AND METHODS: Group A taking vitamin D (250IU/day) and calcium (500 mg/day) supplementation, and Group B were not taking oral supplementation. All subjects had at least one or more teeth with chronic moderate periodontitis. Digital Orthopantomogram images were taken to assess bone density. Data were collected at baseline and three months.
STATISTICAL ANALYSIS USED: OHI-S, GI, PPD, CAL, and Bone Densities (BD) were calculated per group. Karl Pearson Coefficient of correlation was used to test correlation of bone density with GI and OHI -S. Intergroup comparison of parameters were done using Independent two Sample t-test. Intragroup comparison of parameters at recall interval was done using Paired sample t-test. The results were considered statistically significant when p-value was <0.05.
RESULTS: Both Groups showed significant change in the periodontal parameters and bone density after three months and intragroup comparison showed highly significant results for vitamin D group in relation to GI, OHI S and bone density.
CONCLUSION: Calcium and vitamin D supplementation has got a positive effect on periodontal health and it can be used as an adjunct to non surgical periodontal therapy.
Keywords: Calcium carbonate; Cholecalciferol; Recolonization
References
- Lancet. 1973 Jul;2(7822):167-71 - PubMed
- J Bone Miner Res. 2008 Nov;23 (11):1789-97 - PubMed
- J Periodontol. 1967 Nov-Dec;38(6):Suppl:610-6 - PubMed
- J Dent Res. 2011 Aug;90(8):1007-12 - PubMed
- Infect Immun. 2011 Jun;79(6):2250-6 - PubMed
- Arch Osteoporos. 2009 Dec;4(1-2):47-53 - PubMed
- J Assoc Physicians India. 2008 Oct;56:755-7 - PubMed
- Cancer Res. 2006 Apr 15;66(8):4516-24 - PubMed
- Cell Immunol. 1986 Apr 1;98(2):311-22 - PubMed
- J Periodontol. 1990 Sep;61(9):579-84 - PubMed
- Indian J Med Res. 2008 Mar;127(3):269-73 - PubMed
- J Immunol. 2004 Sep 1;173(5):2909-12 - PubMed
- Am J Clin Nutr. 2004 Jul;80(1):108-13 - PubMed
- J Am Dent Assoc. 1964 Jan;68:7-13 - PubMed
- Oral Health Prev Dent. 2013;11(1):61-9 - PubMed
- Cell Mol Biol (Noisy-le-grand). 2003 Mar;49(2):277-300 - PubMed
- Indian J Endocrinol Metab. 2013 Sep;17(5):883-9 - PubMed
- Oral Dis. 2012 Apr;18(3):299-306 - PubMed
- Int J Dent. 2012;2012:571590 - PubMed
- J Periodontol. 2005 Sep;76(9):1576-87 - PubMed
- J Periodontol. 2009 Sep;80(9):1433-9 - PubMed
- J Assoc Physicians India. 2011 Nov;59:706-9 - PubMed
- J Oral Sci. 2009 Mar;51(1):11-20 - PubMed
- Cell Host Microbe. 2009 Sep 17;6(3):231-43 - PubMed
- Periodontol 2000. 2009;50:39-51 - PubMed
- Endocr Pract. 2008 Sep;14(6):665-71 - PubMed
- J Periodontal Res. 2007 Oct;42(5):410-9 - PubMed
- J Periodontol. 2011 Jan;82(1):25-32 - PubMed
- J Immunol. 2001 Nov 1;167(9):4974-80 - PubMed
- J Assoc Physicians India. 2011 Nov;59:695-6 - PubMed
- Am J Med. 2001 Oct 15;111(6):452-6 - PubMed
- J Periodontol. 2013 Sep;84(9):1243-56 - PubMed
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