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Jeziorkowska R, Sysa-Jędrzejowska A, Samochocki Z, et al. Topical steroid therapy in atopic dermatitis in theory and practice. Postepy Dermatol Alergol. 2015;32(3):162-6doi: 10.5114/pdia.2014.40962.
Jeziorkowska, R., Sysa-Jędrzejowska, A., Samochocki, Z., Creaco, E., Franchini, M., & Alvisi, S. (2015). Topical steroid therapy in atopic dermatitis in theory and practice. Postepy dermatologii i alergologii, 32(3), 162-6. https://doi.org/10.5114/pdia.2014.40962
Jeziorkowska, Renata, et al. "Topical steroid therapy in atopic dermatitis in theory and practice." Postepy dermatologii i alergologii vol. 32,3 (2015): 162-6. doi: https://doi.org/10.5114/pdia.2014.40962
Jeziorkowska R, Sysa-Jędrzejowska A, Samochocki Z, Creaco E, Franchini M, Alvisi S. Topical steroid therapy in atopic dermatitis in theory and practice. Postepy Dermatol Alergol. 2015 Jun;32(3):162-6. doi: 10.5114/pdia.2014.40962. Epub 2015 Jun 10. PMID: 26161055; PMCID: PMC4495104.
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Postepy Dermatol Alergol. 2015 Jun;32(3):162-6. doi: 10.5114/pdia.2014.40962. Epub 2015 Jun 10.

Topical steroid therapy in atopic dermatitis in theory and practice.

Postepy dermatologii i alergologii

Renata Jeziorkowska, Anna Sysa-Jędrzejowska, Zbigniew Samochocki, Creaco, Franchini, Alvisi

Affiliations

  1. Department of Dermatology, Medical University of Warsaw, Warsaw, Poland. Head of the Department: Prof. Lidia Rudnicka MD, PhD.
  2. Department of Dermatology, University of Social Sciences, Lodz, Poland. Head of the Department: Prof. Franciszek Seneczko MD, PhD.

PMID: 26161055 PMCID: PMC4495104 DOI: 10.5114/pdia.2014.40962

Abstract

INTRODUCTION: Topical glucocorticosteroids (GCSs) are commonly used in treatment of atopic dermatitis (AD).

AIM: To assess the patients' compliance with the recommended instructions of the therapy.

MATERIAL AND METHODS: The study involved 141 adult AD patients. The clinical course of AD and its treatment with GCSs during the last year were analysed.

RESULTS: In the periods of exacerbation the lesions involved 10-50% of the skin surface area. Outpatient treatment in specialised dermatological and/or allergology clinics was given to 93% of the study subjects. Sixty-five out of 141 patients regularly attended medical control examinations. Glucocorticosteroids, mostly very potent ones (70.2%), were applied to all the subjects. 66.7% of patients obtained no information about their medications' anti-inflammatory potential. The substances were applied more frequently than twice daily by 36.4% of the patients. Seventy-two of 141 subjects applied GCSs both temporarily and in the long-term treatment, for 8.3 weeks on average. In the long-term treatment, in which very potent GCSs predominated (70.7%), no one used intermittent therapy. One hundred and thirty patients introduced their own modifications to the instructions concerning GCSs use, among which 37.7% changed the site of application, 58.5% prolonged the duration of application and 49.5% shortened it or occasionally temporarily withdrew the prescribed drug. None of the patients knew the fingertip unit method of dose assessment. Apart from steroid therapy, 56.7% of the patients carried out regular care treatment.

CONCLUSIONS: The AD patients need to be thoroughly educated by the medical staff in the topical GCSs therapy in atopic dermatitis.

Keywords: atopic dermatitis; glucocorticosteroids; topical treatment

References

  1. J Invest Dermatol. 2003 Mar;120(3):456-64 - PubMed
  2. Br J Dermatol. 2008 May;158(5):917-20 - PubMed
  3. J Am Acad Dermatol. 2006 Jan;54(1):1-15; quiz 16-8 - PubMed
  4. Br J Dermatol. 1997 Jun;136(6):884-90 - PubMed
  5. Br J Dermatol. 2000 May;142(5):931-6 - PubMed
  6. Dermatology. 2007;214(1):61-7 - PubMed
  7. Pediatr Dermatol. 2013 May-Jun;30(3):329-34 - PubMed
  8. J Invest Dermatol. 2009 Aug;129(8):1878-91 - PubMed
  9. BMJ. 2006 Apr 22;332(7547):933-8 - PubMed
  10. Clin Exp Dermatol. 1991 Nov;16(6):444-7 - PubMed
  11. Clin Dermatol. 2003 May-Jun;21(3):193-200 - PubMed
  12. Mediators Inflamm. 1998;7(3):183-93 - PubMed
  13. J Invest Dermatol. 2009 Jan;129(1):14-30 - PubMed
  14. Clin Exp Dermatol. 2003 Sep;28(5):549-53 - PubMed
  15. J Am Acad Dermatol. 1996 Oct;35(4):615-9 - PubMed
  16. J Invest Dermatol. 2009 Aug;129(8):1892-908 - PubMed
  17. J Am Acad Dermatol. 2004 Mar;50(3):391-404 - PubMed
  18. J Eur Acad Dermatol Venereol. 2010 Mar;24(3):317-28 - PubMed
  19. Wiad Lek. 2005;58(11-12):607-15 - PubMed

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