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Tajika M, Nakamura T, Tsuboi J, et al. Syndrome of inappropriate secretion of antidiuretic hormone after endoscopic submucosal dissection for early gastric cancer. Clin J Gastroenterol. 2009;2(4):262-265doi: 10.1007/s12328-009-0085-9.
Tajika, M., Nakamura, T., Tsuboi, J., Bhatia, V., Kawai, H., & Yamao, K. (2009). Syndrome of inappropriate secretion of antidiuretic hormone after endoscopic submucosal dissection for early gastric cancer. Clinical journal of gastroenterology, 2(4), 262-265. https://doi.org/10.1007/s12328-009-0085-9
Tajika, Masahiro, et al. "Syndrome of inappropriate secretion of antidiuretic hormone after endoscopic submucosal dissection for early gastric cancer." Clinical journal of gastroenterology vol. 2,4 (2009): 262-265. doi: https://doi.org/10.1007/s12328-009-0085-9
Tajika M, Nakamura T, Tsuboi J, Bhatia V, Kawai H, Yamao K. Syndrome of inappropriate secretion of antidiuretic hormone after endoscopic submucosal dissection for early gastric cancer. Clin J Gastroenterol. 2009 Aug;2(4):262-265. doi: 10.1007/s12328-009-0085-9. Epub 2009 May 02. PMID: 26192421.
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Clin J Gastroenterol. 2009 Aug;2(4):262-265. doi: 10.1007/s12328-009-0085-9. Epub 2009 May 02.

Syndrome of inappropriate secretion of antidiuretic hormone after endoscopic submucosal dissection for early gastric cancer.

Clinical journal of gastroenterology

Masahiro Tajika, Tsuneya Nakamura, Junya Tsuboi, Vikram Bhatia, Hiroki Kawai, Kenji Yamao

Affiliations

  1. Department of Endoscopy, Aichi Cancer Center Hospital, 1-1 Kanokoden, Chikusa-ku, Nagoya, 464-8681, Japan. [email protected].
  2. Department of Endoscopy, Aichi Cancer Center Hospital, 1-1 Kanokoden, Chikusa-ku, Nagoya, 464-8681, Japan.
  3. Department of Gastroenterology, Aichi Cancer Center Hospital, Nagoya, Japan.
  4. Department of Medical Hepatology, Institute of Liver and Biliary Sciences, New Delhi, India.

PMID: 26192421 DOI: 10.1007/s12328-009-0085-9

Abstract

We report the first case of syndrome of inappropriate secretion of antidiuretic hormone (SIADH) after endoscopic submucosal dissection (ESD) for early gastric cancer. A 64-year-old man with early gastric cancer was admitted to our hospital for ESD. Baseline laboratory tests showed a serum sodium concentration of 132 mEq l(-1). We performed an ESD for the gastric cancer, which was 9 mm in diameter and located in the posterior wall of the mid-gastric body. The patient experienced nausea and lethargy the second day after ESD. His serum sodium level was low (118 mEq l(-1)), and he fulfilled the criteria for SIADH. Fluid restriction, infusion of normal saline, and administration of diuretics gradually increased his serum sodium level, and his symptoms disappeared. Endoscopists should recognize that SIADH is a potential complication of endoscopic procedures such as ESD, especially among patients with low baseline sodium concentrations.

Keywords: Complication; Endoscopic submucosal dissection (ESD); Endoscopic treatment; Gastric cancer; Syndrome of inappropriate secretion of antidiuretic hormone (SIADH)

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