Display options
Cite
Nishikawa N, Nagai M, Tsujii T, et al. Treatment of Myasthenia Gravis in Patients with Elderly Onset at Advanced Age. Jpn Clin Med. 2015;6:9-13doi: 10.4137/JCM.S29601.
Nishikawa, N., Nagai, M., Tsujii, T., Kyaw, W. T., Tanabe, N., Iwaki, H., Yabe, H., Ando, R., & Nomoto, M. (2015). Treatment of Myasthenia Gravis in Patients with Elderly Onset at Advanced Age. Japanese clinical medicine, 69-13. https://doi.org/10.4137/JCM.S29601
Nishikawa, Noriko, et al. "Treatment of Myasthenia Gravis in Patients with Elderly Onset at Advanced Age." Japanese clinical medicine vol. 6 (2015): 9-13. doi: https://doi.org/10.4137/JCM.S29601
Nishikawa N, Nagai M, Tsujii T, Kyaw WT, Tanabe N, Iwaki H, Yabe H, Ando R, Nomoto M. Treatment of Myasthenia Gravis in Patients with Elderly Onset at Advanced Age. Jpn Clin Med. 2015 Jul 23;6:9-13. doi: 10.4137/JCM.S29601. eCollection 2015. PMID: 26279637; PMCID: PMC4514170.
Copy Download .nbib Format: NLM
Share it on

Jpn Clin Med. 2015 Jul 23;6:9-13. doi: 10.4137/JCM.S29601. eCollection 2015.

Treatment of Myasthenia Gravis in Patients with Elderly Onset at Advanced Age.

Japanese clinical medicine

Noriko Nishikawa, Masahiro Nagai, Tomoaki Tsujii, Win T Kyaw, Nachi Tanabe, Hirotaka Iwaki, Hayato Yabe, Rina Ando, Masahiro Nomoto

Affiliations

  1. Department of Neurology and Clinical Pharmacology, Ehime University Graduate School of Medicine, Shitsukawa Tohon, Ehime, Japan.

PMID: 26279637 PMCID: PMC4514170 DOI: 10.4137/JCM.S29601

Abstract

The number of patients with late-onset myasthenia gravis (MG) among patients ≥50 years has been increasing recently. We encountered three patients who developed elderly-onset MG at a particularly advanced age (≥80 years). All were female and positive for anti-acetylcholine receptor antibodies. About 4 years have passed since MG onset in all three patients and symptoms have been controlled without recurrence using a combination of oral low-dose prednisolone and tacrolimus. As many cases of elderly-onset MG do not require strong immunosuppression, we recommend minimum immunosuppressive treatment to avoid adverse events, particularly in patients at an advanced age of ≥80 years.

Keywords: elderly; myasthenia gravis; treatment

References

  1. Intern Med. 2004 Mar;43(3):189-93 - PubMed
  2. Neurology. 2005 Sep 27;65(6):928-30 - PubMed
  3. J Neurol Neurosurg Psychiatry. 2003 Aug;74(8):1105-8 - PubMed
  4. J Neurol Sci. 2011 Jun 15;305(1-2):97-102 - PubMed
  5. J Clin Neurosci. 2007 Feb;14(2):110-5 - PubMed
  6. Rinsho Shinkeigaku. 2011 Aug;51(8):576-82 - PubMed
  7. Intern Med. 2005 Jun;44(6):572-7 - PubMed
  8. J Neurol Neurosurg Psychiatry. 2011 Sep;82(9):970-7 - PubMed

Publication Types