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Zarnescu NO, Iliesiu A, Procop A, et al. A Challenging Case of Primary Breast Hodgkin's Lymphoma. Maedica (Bucur). 2015;10(1):44-7
Zarnescu, N. O., Iliesiu, A., Procop, A., Tampa, M., Matei, C., Sajin, M., Costache, M., Dumitru, A., & Lazaroiu, A. M. (2015). A Challenging Case of Primary Breast Hodgkin's Lymphoma. Maedica, 10(1), 44-7.
Zarnescu, Narcis Octavian, et al. "A Challenging Case of Primary Breast Hodgkin's Lymphoma." Maedica vol. 10,1 (2015): 44-7.
Zarnescu NO, Iliesiu A, Procop A, Tampa M, Matei C, Sajin M, Costache M, Dumitru A, Lazaroiu AM. A Challenging Case of Primary Breast Hodgkin's Lymphoma. Maedica (Bucur). 2015 Mar;10(1):44-7. PMID: 26225149; PMCID: PMC4496765.
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Maedica (Bucur). 2015 Mar;10(1):44-7.

A Challenging Case of Primary Breast Hodgkin's Lymphoma.

Maedica

Narcis Octavian Zarnescu, Andreea Iliesiu, Alexandru Procop, Mircea Tampa, Clara Matei, Maria Sajin, Mariana Costache, Adrian Dumitru, Anca Mihaela Lazaroiu

Affiliations

  1. Department of Surgery, Emergency University Hospital, "Carol Davila" University of Medicine and Pharmacy, Bucharest, Romania.
  2. Department of Pathology, Emergency University Hospital, "Carol Davila" University of Medicine and Pharmacy, Bucharest, Romania.
  3. Department of Pathology, Emergency University Hospital, Bucharest, Romania.
  4. Department of Dermatology II, "Colentina" Clinical Hospital, Bucharest, Romania.

PMID: 26225149 PMCID: PMC4496765

Abstract

Primary breast lymphoma (PBL) is a rare entity accounting for less than 1% of all breast malignancies. Diagnostic criteria for primary Hodgkin's lymphoma of the breast are: the presence of sufficient tissue for diagnosis, close interaction between mammary tissue and lymphomatous infiltrate and no evidence or prior diagnosis of widespread lymphoma. Our case illustrates an unusual presentation of Hodgkin's lymphoma of the breast: clinically as inflammatory breast cancer and core biopsy as granulomatous mastitis, the final diagnosis requiring surgical biopsy. Current information regarding this entity is scant, mainly build upon its rarity. In this paper we assess the clinical presentation, the step-by-step diagnosis, the treatment and the importance of immunohistochemistry in this uncommon condition.

Keywords: extranodal Hodgkin's lymphoma; immunohistochemistry; primary breast lymphoma

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