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Mague JT, Mohamed SK, Akkurt M, et al. Crystal structure of ethyl (4R)-2-amino-7-hy-droxy-4-phenyl-4H-chromene-3-carboxyl-ate. Acta Crystallogr E Crystallogr Commun. 2015;71:o519-20doi: 10.1107/S2056989015012013.
Mague, J. T., Mohamed, S. K., Akkurt, M., Younes, S. H., & Albayati, M. R. (2015). Crystal structure of ethyl (4R)-2-amino-7-hy-droxy-4-phenyl-4H-chromene-3-carboxyl-ate. Acta crystallographica. Section E, Crystallographic communications, 71o519-20. https://doi.org/10.1107/S2056989015012013
Mague, Joel T, et al. "Crystal structure of ethyl (4R)-2-amino-7-hy-droxy-4-phenyl-4H-chromene-3-carboxyl-ate." Acta crystallographica. Section E, Crystallographic communications vol. 71 (2015): o519-20. doi: https://doi.org/10.1107/S2056989015012013
Mague JT, Mohamed SK, Akkurt M, Younes SH, Albayati MR. Crystal structure of ethyl (4R)-2-amino-7-hy-droxy-4-phenyl-4H-chromene-3-carboxyl-ate. Acta Crystallogr E Crystallogr Commun. 2015 Jun 27;71:o519-20. doi: 10.1107/S2056989015012013. eCollection 2015 Jul 01. PMID: 26279941; PMCID: PMC4518989.
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Acta Crystallogr E Crystallogr Commun. 2015 Jun 27;71:o519-20. doi: 10.1107/S2056989015012013. eCollection 2015 Jul 01.

Crystal structure of ethyl (4R)-2-amino-7-hy-droxy-4-phenyl-4H-chromene-3-carboxyl-ate.

Acta crystallographica. Section E, Crystallographic communications

Joel T Mague, Shaaban K Mohamed, Mehmet Akkurt, Sabry H H Younes, Mustafa R Albayati

Affiliations

  1. Department of Chemistry, Tulane University, New Orleans, LA 70118, USA.
  2. Faculty of Science & Engineering, School of Healthcare Science, Manchester Metropolitan University, Manchester M1 5GD, England ; Chemistry Department, Faculty of Science, Minia University, 61519 El-Minia, Egypt.
  3. Department of Physics, Faculty of Sciences, Erciyes University, 38039 Kayseri, Turkey.
  4. Chemistry Department, Faculty of Science, Sohag University, 82524 Sohag, Egypt.
  5. Kirkuk University, College of Education, Department of Chemistry, Kirkuk, Iraq.

PMID: 26279941 PMCID: PMC4518989 DOI: 10.1107/S2056989015012013

Abstract

In the title compound, C18H17NO4, the dihedral angle between the phenyl ring and the fused six-membered ring is 77.65 (4)°. The conformation of the mol-ecule is determined in part by an intra-molecular N-H⋯O hydrogen bond between the amino H atom and the carbonyl O atom, forming an S(6) motif. In the crystal, mol-ecules are linked into N-H⋯O hydrogen-bonded inversion dimers which are then connected into chains along [001], forming a two-dimensional network parallel to (100) via O-H⋯O hydrogen bonds. C-H⋯O interactions further contribute to the crystal stability. The ethyl group is disordered over two sets of sites in a 0.801 (5):0.199 (5) ratio.

Keywords: 4H-chromene; amino chromenes; crystal structure; hydrogen bonding

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