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Salameh A, Bello N, Becker J, et al. Fatal Granulomatous Amoebic Encephalitis Caused by Acanthamoeba in a Patient With Kidney Transplant: A Case Report. Open Forum Infect Dis. 2015;2(3):ofv104doi: 10.1093/ofid/ofv104.
Salameh, A., Bello, N., Becker, J., & Zangeneh, T. (2015). Fatal Granulomatous Amoebic Encephalitis Caused by Acanthamoeba in a Patient With Kidney Transplant: A Case Report. Open forum infectious diseases, 2(3), ofv104. https://doi.org/10.1093/ofid/ofv104
Salameh, Ahmad, et al. "Fatal Granulomatous Amoebic Encephalitis Caused by Acanthamoeba in a Patient With Kidney Transplant: A Case Report." Open forum infectious diseases vol. 2,3 (2015): ofv104. doi: https://doi.org/10.1093/ofid/ofv104
Salameh A, Bello N, Becker J, Zangeneh T. Fatal Granulomatous Amoebic Encephalitis Caused by Acanthamoeba in a Patient With Kidney Transplant: A Case Report. Open Forum Infect Dis. 2015 Jul 10;2(3):ofv104. doi: 10.1093/ofid/ofv104. eCollection 2015 Sep. PMID: 26280011; PMCID: PMC4534522.
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Open Forum Infect Dis. 2015 Jul 10;2(3):ofv104. doi: 10.1093/ofid/ofv104. eCollection 2015 Sep.

Fatal Granulomatous Amoebic Encephalitis Caused by Acanthamoeba in a Patient With Kidney Transplant: A Case Report.

Open forum infectious diseases

Ahmad Salameh, Nancy Bello, Jennifer Becker, Tirdad Zangeneh

Affiliations

  1. Division of Infectious Diseases, Department of Medicine.
  2. Departments of Neurology.
  3. Radiology , University of Arizona , Tucson.

PMID: 26280011 PMCID: PMC4534522 DOI: 10.1093/ofid/ofv104

Abstract

Granulomatous amoebic encephalitis (GAE) due to Acanthamoeba is almost a uniformly fatal infection in immune-compromised hosts despite multidrug combination therapy. We report a case of GAE in a female who received a deceased donor kidney graft. She was treated with a combination of miltefosine, pentamidine, sulfadiazine, fluconazole, flucytosine, and azithromycin.

Keywords: Acanthamoeba; encephalitis; granulomatous amoebic; immunosuppression; transplantation

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