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Chem Commun (Camb). 2015 Nov 04;51(85):15578-81. doi: 10.1039/c5cc06475a.

Multicomponent ternary cocrystals of the sulfonamide group with pyridine-amides and lactams.

Chemical communications (Cambridge, England)

Geetha Bolla, Ashwini Nangia

Affiliations

  1. School of Chemistry, University of Hyderabad, Prof. C. R. Rao Road, Central University P.O., Hyderabad 500046, India. [email protected].

PMID: 26355724 DOI: 10.1039/c5cc06475a

Abstract

SMBA was selected as a bifunctional sulfa drug to design ternary cocrystals with pyridine amides and lactam coformers. Supramolecular assembly of five ternary cocrystals of p-sulfonamide benzoic acid with nicotinamide and 2-pyridone is demonstrated and reproducible heterosynthons are identified for crystal engineering.

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