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Herranz D, Lloret J, Jiménez-Valero S, et al. Novel catheter enabling simultaneous radiofrequency ablation and optical coherence reflectometry. Biomed Opt Express. 2015;6(9):3268-75doi: 10.1364/BOE.6.003268.
Herranz, D., Lloret, J., Jiménez-Valero, S., Rubio-Guivernau, J. L., & Margallo-Balbás, E. (2015). Novel catheter enabling simultaneous radiofrequency ablation and optical coherence reflectometry. Biomedical optics express, 6(9), 3268-75. https://doi.org/10.1364/BOE.6.003268
Herranz, D, et al. "Novel catheter enabling simultaneous radiofrequency ablation and optical coherence reflectometry." Biomedical optics express vol. 6,9 (2015): 3268-75. doi: https://doi.org/10.1364/BOE.6.003268
Herranz D, Lloret J, Jiménez-Valero S, Rubio-Guivernau JL, Margallo-Balbás E. Novel catheter enabling simultaneous radiofrequency ablation and optical coherence reflectometry. Biomed Opt Express. 2015 Aug 07;6(9):3268-75. doi: 10.1364/BOE.6.003268. eCollection 2015 Sep 01. PMID: 26417499; PMCID: PMC4574655.
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Biomed Opt Express. 2015 Aug 07;6(9):3268-75. doi: 10.1364/BOE.6.003268. eCollection 2015 Sep 01.

Novel catheter enabling simultaneous radiofrequency ablation and optical coherence reflectometry.

Biomedical optics express

D Herranz, Juan Lloret, Santiago Jiménez-Valero, J L Rubio-Guivernau, Eduardo Margallo-Balbás

Affiliations

  1. Medlumics S.L, Ronda de Poniente 6, 2A-B, 28760 Tres Cantos, Spain.
  2. Medlumics S.L, Ronda de Poniente 6, 2A-B, 28760 Tres Cantos, Spain ; Servicio de Cardiología Intervencionista, Hospital Universitario La Paz, Madrid, Spain.

PMID: 26417499 PMCID: PMC4574655 DOI: 10.1364/BOE.6.003268

Abstract

A novel radiofrequency ablation catheter has been developed with integrated custom designed optics, enabling real-time monitoring of radiofrequency ablation procedures through polarization-sensitive optical coherence reflectometry. The optics allow for proper tissue illumination through a view-port machined in the catheter tip, thus providing lesion depth control over the RF ablation treatment. The system was verified in an in-vitro model of swine myocardium. Optical performance and thermal stability was confirmed after more than 25 procedures, without any damage to the optical assembly induced by thermal stress or material degradation. The use of this catheter in RF ablation treatments may make possible to assess lesion depth during therapy, thus translating into a reduction of potential complications on the procedure.

Keywords: (110.4500) Optical coherence tomography; (120.4570) Optical design of instruments; (170.1020) Ablation of tissue; (170.3890) Medical optics instrumentation

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