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Yang X, Chen H, Li S, et al. Association of Sleep Duration with the Morbidity and Mortality of Coronary Artery Disease: A Meta-analysis of Prospective Studies. Heart Lung Circ. 2015;24(12):1180-90doi: 10.1016/j.hlc.2015.08.005.
Yang, X., Chen, H., Li, S., Pan, L., & Jia, C. (2015). Association of Sleep Duration with the Morbidity and Mortality of Coronary Artery Disease: A Meta-analysis of Prospective Studies. Heart, lung & circulation, 24(12), 1180-90. https://doi.org/10.1016/j.hlc.2015.08.005
Yang, Xiaorong, et al. "Association of Sleep Duration with the Morbidity and Mortality of Coronary Artery Disease: A Meta-analysis of Prospective Studies." Heart, lung & circulation vol. 24,12 (2015): 1180-90. doi: https://doi.org/10.1016/j.hlc.2015.08.005
Yang X, Chen H, Li S, Pan L, Jia C. Association of Sleep Duration with the Morbidity and Mortality of Coronary Artery Disease: A Meta-analysis of Prospective Studies. Heart Lung Circ. 2015 Dec;24(12):1180-90. doi: 10.1016/j.hlc.2015.08.005. Epub 2015 Sep 07. PMID: 26422535.
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Heart Lung Circ. 2015 Dec;24(12):1180-90. doi: 10.1016/j.hlc.2015.08.005. Epub 2015 Sep 07.

Association of Sleep Duration with the Morbidity and Mortality of Coronary Artery Disease: A Meta-analysis of Prospective Studies.

Heart, lung & circulation

Xiaorong Yang, Hui Chen, Suyun Li, Lulu Pan, Chongqi Jia

Affiliations

  1. Department of Epidemiology and Biostatistics, Shandong University, Jinan 250012, Shandong, P.R. China.
  2. Department of Epidemiology and Biostatistics, Shandong University, Jinan 250012, Shandong, P.R. China. Electronic address: [email protected].

PMID: 26422535 DOI: 10.1016/j.hlc.2015.08.005

Abstract

PURPOSE: Insufficient and excessive sleep duration have become increasingly common in modern society. Published literatures report controversial results about the association of sleep duration with coronary artery disease (CAD).

METHODS: A comprehensive search was performed to identify related prospective studies providing quantitative estimates between sleep duration and CAD. Meta-analysis was applied to calculate the combined relative risks (RRs) with 95% confidence intervals (CI) for sleep with morbidity and mortality of CAD. The risk of bias was assessed by the Egger regression asymmetry test.

RESULTS: Fifteen studies conformed to the criteria. Compared with normal sleep duration, the pooled RRs (95%CI) of short sleep duration were 1.10(1.04-1.17) and 1.25(1.06-1.47) for the morbidity and mortality of CAD, and the pooled RRs (95%CI) of long sleep duration were 1.03(0.92-1.16) and 1.26(1.11-1.42) for the morbidity and mortality of CAD, respectively. The effect of short and long sleep duration on mortality of CAD were always significantly greater than the morbidity of CAD.

CONCLUSIONS: Short sleep duration was associated with higher morbidity of CAD, and short sleepers and long sleepers had higher risk for CAD mortality. Keeping normal sleep duration is an appropriate recommendation to prevent and control CAD.

Copyright © 2015 Australian and New Zealand Society of Cardiac and Thoracic Surgeons (ANZSCTS) and the Cardiac Society of Australia and New Zealand (CSANZ). Published by Elsevier B.V. All rights reserved.

Keywords: Coronary artery disease; Meta-analysis; Prevention; Sleep; Sleep duration

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