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World J Radiol. 2015 Aug 28;7(8):202-11. doi: 10.4329/wjr.v7.i8.202.

Imaging of bone metastasis: An update.

World journal of radiology

Gerard J O'Sullivan, Fiona L Carty, Carmel G Cronin

Affiliations

  1. Gerard J O'Sullivan, Fiona L Carty, Carmel G Cronin, Department of Radiology, Mater Misericordiae University Hospital, Dublin 7, Ireland.

PMID: 26339464 PMCID: PMC4553252 DOI: 10.4329/wjr.v7.i8.202

Abstract

Early detection of skeletal metastasis is critical for accurate staging and optimal treatment. This paper briefly reviews our current understanding of the biological mechanisms through which tumours metastasise to bone and describes the available imaging methods to diagnose bone metastasis and monitor response to treatment. Among the various imaging modalities currently available for imaging skeletal metastasis, hybrid techniques which fuse morphological and functional data are the most sensitive and specific, and positron emission tomography (PET)/computed tomography and PET/magnetic resonance imaging will almost certainly continue to evolve and become increasingly important in this regard.

Keywords: Bone and bones; Computed tomography; Magnetic resonance imaging; Neoplasm metastasis; Radionuclide imaging

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