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Kamimura K, Yokoo T, Abe H, et al. Image-Guided Hydrodynamic Gene Delivery: Current Status and Future Directions. Pharmaceutics. 2015;7(3):213-23doi: 10.3390/pharmaceutics7030213.
Kamimura, K., Yokoo, T., Abe, H., Kobayashi, Y., Ogawa, K., Shinagawa, Y., Inoue, R., & Terai, S. (2015). Image-Guided Hydrodynamic Gene Delivery: Current Status and Future Directions. Pharmaceutics, 7(3), 213-23. https://doi.org/10.3390/pharmaceutics7030213
Kamimura, Kenya, et al. "Image-Guided Hydrodynamic Gene Delivery: Current Status and Future Directions." Pharmaceutics vol. 7,3 (2015): 213-23. doi: https://doi.org/10.3390/pharmaceutics7030213
Kamimura K, Yokoo T, Abe H, Kobayashi Y, Ogawa K, Shinagawa Y, Inoue R, Terai S. Image-Guided Hydrodynamic Gene Delivery: Current Status and Future Directions. Pharmaceutics. 2015 Aug 21;7(3):213-23. doi: 10.3390/pharmaceutics7030213. PMID: 26308044; PMCID: PMC4588196.
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Pharmaceutics. 2015 Aug 21;7(3):213-23. doi: 10.3390/pharmaceutics7030213.

Image-Guided Hydrodynamic Gene Delivery: Current Status and Future Directions.

Pharmaceutics

Kenya Kamimura, Takeshi Yokoo, Hiroyuki Abe, Yuji Kobayashi, Kohei Ogawa, Yoko Shinagawa, Ryosuke Inoue, Shuji Terai

Affiliations

  1. Division of Gastroenterology and Hepatology, Graduate School of Medical and Dental Sciences, Niigata University, Niigata 951-8510, Japan. [email protected].
  2. Division of Gastroenterology and Hepatology, Graduate School of Medical and Dental Sciences, Niigata University, Niigata 951-8510, Japan. [email protected].
  3. Division of Gastroenterology and Hepatology, Graduate School of Medical and Dental Sciences, Niigata University, Niigata 951-8510, Japan. [email protected].
  4. Division of Gastroenterology and Hepatology, Graduate School of Medical and Dental Sciences, Niigata University, Niigata 951-8510, Japan. [email protected].
  5. Division of Gastroenterology and Hepatology, Graduate School of Medical and Dental Sciences, Niigata University, Niigata 951-8510, Japan. [email protected].
  6. Division of Gastroenterology and Hepatology, Graduate School of Medical and Dental Sciences, Niigata University, Niigata 951-8510, Japan. [email protected].
  7. Division of Gastroenterology and Hepatology, Graduate School of Medical and Dental Sciences, Niigata University, Niigata 951-8510, Japan. [email protected].
  8. Division of Gastroenterology and Hepatology, Graduate School of Medical and Dental Sciences, Niigata University, Niigata 951-8510, Japan. [email protected].

PMID: 26308044 PMCID: PMC4588196 DOI: 10.3390/pharmaceutics7030213

Abstract

Hydrodynamics-based delivery has been used as an experimental tool to express transgene in small animals. This in vivo gene transfer method is useful for functional analysis of genetic elements, therapeutic effect of oligonucleotides, and cancer cells to establish the metastatic cancer animal model for experimental research. Recent progress in the development of image-guided procedure for hydrodynamics-based gene delivery in large animals directly supports the clinical applicability of this technique. This review summarizes the current status and recent progress in the development of hydrodynamics-based gene delivery and discusses the future directions for its clinical application.

Keywords: DNA; clinical application; gene therapy; hydrodynamics-based gene delivery

References

  1. Gene Ther. 2006 Dec;13(24):1696-702 - PubMed
  2. Virol J. 2013 Jun 28;10:214 - PubMed
  3. PLoS One. 2012;7(12):e52370 - PubMed
  4. J Gene Med. 2007 Jun;9(6):488-97 - PubMed
  5. Mol Imaging Biol. 2014 Apr;16(2):224-34 - PubMed
  6. Atherosclerosis. 2011 Mar;215(1):34-42 - PubMed
  7. Mol Ther. 2007 Dec;15(12):2063-9 - PubMed
  8. Gene Ther. 2004 Apr;11(8):675-82 - PubMed
  9. J Gene Med. 2007 Nov;9(11):976-85 - PubMed
  10. ScientificWorldJournal. 2011;11:2480-90 - PubMed
  11. Dig Dis Sci. 2012 Apr;57(4):925-34 - PubMed
  12. Nature. 2003 Jan 23;421(6921):305 - PubMed
  13. J Mol Histol. 2013 Oct;44(5):535-44 - PubMed
  14. Mol Ther. 2009 Mar;17(3):491-9 - PubMed
  15. J Gene Med. 2013 Feb;15(2):65-77 - PubMed
  16. Proc Natl Acad Sci U S A. 2007 Sep 11;104(37):14771-6 - PubMed
  17. J Endocrinol. 2012 Sep;214(3):277-88 - PubMed
  18. Mol Ther Nucleic Acids. 2013 Oct 15;2:e128 - PubMed
  19. PLoS One. 2013 Sep 26;8(9):e75462 - PubMed
  20. Comp Hepatol. 2007 Oct 19;6:9 - PubMed
  21. Hum Gene Ther. 1999 Jul 1;10(10):1735-7 - PubMed
  22. Gene Ther. 1999 Jul;6(7):1258-66 - PubMed
  23. Pharmaceut Med. 2011 Oct 1;25(5):293-306 - PubMed
  24. Cancer Biol Ther. 2011 Oct 15;12(8):737-41 - PubMed
  25. J Am Soc Nephrol. 2004 Jun;15(6):1430-40 - PubMed
  26. J Immunol. 2013 Sep 15;191(6):3264-76 - PubMed
  27. Endocr J. 2008 Dec;55(6):1033-41 - PubMed
  28. J Virol. 2001 Apr;75(7):3469-73 - PubMed
  29. Gene Ther. 2012 Sep;19(9):877-85 - PubMed
  30. Blood. 2013 Jun 27;121(26):5228-37 - PubMed
  31. PLoS One. 2014 Sep 24;9(9):e107203 - PubMed
  32. Hum Gene Ther. 2003 Sep 20;14(14):1297-305 - PubMed
  33. Antimicrob Agents Chemother. 2013 Nov;57(11):5366-72 - PubMed
  34. Clin Exp Med. 2014 Nov;14(4):397-408 - PubMed
  35. Gene Ther. 2003 Dec;10(25):2059-66 - PubMed
  36. Pharm Res. 2011 Apr;28(4):694-701 - PubMed
  37. Proc Natl Acad Sci U S A. 2004 Jun 8;101(23):8682-6 - PubMed
  38. Mol Pharm. 2013 Oct 7;10(10):3812-21 - PubMed
  39. Gene Ther. 2008 Mar;15(6):452-62 - PubMed
  40. Antioxid Redox Signal. 2013 Dec 1;19(16):1889-901 - PubMed
  41. Proc Natl Acad Sci U S A. 2003 Jun 24;100(13):7797-802 - PubMed
  42. Liver Int. 2008 Dec;28(10):1446-57 - PubMed
  43. Am J Physiol Renal Physiol. 2011 Oct;301(4):F784-92 - PubMed
  44. Hepatology. 2013 Jan;57(1):277-88 - PubMed
  45. Mol Ther. 2013 Oct;21(10):1889-97 - PubMed
  46. Mol Ther. 2008 Jun;16(6):1098-104 - PubMed
  47. Nature. 2002 Jul 4;418(6893):38-9 - PubMed
  48. Gene Ther. 2000 Aug;7(15):1344-9 - PubMed
  49. Mol Ther. 2013 Oct;21(10):1852-61 - PubMed
  50. Gene Ther. 2013 May;20(5):538-44 - PubMed
  51. J Hepatol. 2012 Sep;57(3):577-83 - PubMed
  52. Gene Ther. 2007 Jan;14(2):129-37 - PubMed
  53. J Hepatol. 2009 Mar;50(3):479-88 - PubMed
  54. Gene Ther. 2013 Aug;20(8):816-23 - PubMed
  55. Mol Ther. 2010 Jan;18(1):93-100 - PubMed
  56. Gene Ther. 2009 Jun;16(6):746-56 - PubMed
  57. Methods Mol Biol. 2008;442:67-73 - PubMed
  58. Science. 1999 Dec 17;286(5448):2244-5 - PubMed
  59. Gene Ther. 2013 Aug;20(8):846-52 - PubMed
  60. J Gene Med. 2008 May;10(5):551-63 - PubMed
  61. Arthritis Rheum. 2008 Feb;58(2):413-21 - PubMed
  62. Cell Physiol Biochem. 2011;27(6):641-52 - PubMed
  63. Proc Natl Acad Sci U S A. 2009 Nov 17;106(46):19509-14 - PubMed
  64. AAPS J. 2008 Dec;10(4):589-95 - PubMed
  65. Am J Pathol. 2012 Dec;181(6):2105-13 - PubMed
  66. Hum Gene Ther. 2010 Feb;21(2):221-37 - PubMed
  67. Gene Ther. 2007 Feb;14(4):334-43 - PubMed
  68. Hum Gene Ther. 2002 Nov 20;13(17):2065-77 - PubMed

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