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Proc (Bayl Univ Med Cent). 2015 Oct;28(4):494-5. doi: 10.1080/08998280.2015.11929320.

Iron deficiency and hemolytic anemia reversed by ventricular septal myectomy.

Proceedings (Baylor University. Medical Center)

Sudhir Thotakura, Steven M Costa, Christian Cable

Affiliations

  1. Department of Internal Medicine (Thotakura, Cable) and the Division of Cardiology (Costa), Baylor Scott & White Health and Texas A&M Health Science Center College of Medicine, Temple, Texas.

PMID: 26424952 PMCID: PMC4569235 DOI: 10.1080/08998280.2015.11929320

Abstract

Hemolytic anemia has been reported to occur in the setting of aortic stenosis and prosthetic heart valves, but much more rarely in association with obstructive hypertrophic cardiomyopathy (HC). Of the few descriptions of hemolytic anemia secondary to HC, all but one case involved bacterial endocarditis contributing to left ventricular outflow tract obstruction. We present the case of a 67-year-old man with recurrent hemolytic anemia and HC, without infective endocarditis. Attempts at iron repletion and augmentation of beta-blocker therapy proved his anemia to be refractory to medical management. Ventricular septal myectomy led to the resolution of hemolysis, anemia, and its coexisting symptoms.

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