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Can Urol Assoc J. 2015 Sep-Oct;9(9):E683-6. doi: 10.5489/cuaj.3008. Epub 2015 Sep 09.

Fungus ball and emphysematous cystitis secondary to Candida tropicalis: A case report.

Canadian Urological Association journal = Journal de l'Association des urologues du Canada

Lei Wang, Xiang Ji, Guo-Feng Sun, Ying-Chao Qin, Miao-Zi Gong, Jin-Xia Zhang, Ning-Chen Li, Yan-Qun Na

Affiliations

  1. Wu-Jieping Urology Center, Peking University Shougang Hospital, Peking University Health Science Center, Beijing, China;
  2. Department of Pathology, Peking University Shougang Hospital, Peking University Health Science Center, Beijing, China.

PMID: 26425243 PMCID: PMC4581947 DOI: 10.5489/cuaj.3008

Abstract

Fungus ball and fungal emphysematous cystitis are two rare complications of fungal urinary tract infection. A 53-year-old male patient presented with these complications caused by Candida tropicalis simultaneously. The predisposing factors were diabetes mellitus and usage of broad-spectrum antibiotics. The fungus ball, measuring 3.5 × 2.0 cm on the left wall of the urinary bladder, shrank significantly to 1.6 × 0.8 cm after 5 days of intermittent irrigation with saline before surgery. With transurethral removal of the fungus ball and antifungal treatment with fluconazole, the patient fully recovered. We conclude that a bladder fungus ball and fungal emphysematous cystitis should always be suspected in patients with diabetes mellitus with uncontrolled funguria and abnormal imaging. Treatment should include a systemic antifungal therapy and thorough surgical removal of the fungus ball. A systemic antifungal therapy combined with a local irrigation with saline or antifungal drugs might help decrease the dissemination of fungemia during an invasive manipulation.

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