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Feizi S, Javadi MA, Javadi F, et al. Deep Anterior Lamellar Keratoplasty in Keratoconic Patients with versus without Vernal Keratoconjunctivitis. J Ophthalmic Vis Res. 2015;10(2):112-7doi: 10.4103/2008-322X.163768.
Feizi, S., Javadi, M. A., Javadi, F., & Jafarinasab, M. R. (2015). Deep Anterior Lamellar Keratoplasty in Keratoconic Patients with versus without Vernal Keratoconjunctivitis. Journal of ophthalmic & vision research, 10(2), 112-7. https://doi.org/10.4103/2008-322X.163768
Feizi, Sepehr, et al. "Deep Anterior Lamellar Keratoplasty in Keratoconic Patients with versus without Vernal Keratoconjunctivitis." Journal of ophthalmic & vision research vol. 10,2 (2015): 112-7. doi: https://doi.org/10.4103/2008-322X.163768
Feizi S, Javadi MA, Javadi F, Jafarinasab MR. Deep Anterior Lamellar Keratoplasty in Keratoconic Patients with versus without Vernal Keratoconjunctivitis. J Ophthalmic Vis Res. 2015 Apr-Jun;10(2):112-7. doi: 10.4103/2008-322X.163768. PMID: 26425311; PMCID: PMC4568606.
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J Ophthalmic Vis Res. 2015 Apr-Jun;10(2):112-7. doi: 10.4103/2008-322X.163768.

Deep Anterior Lamellar Keratoplasty in Keratoconic Patients with versus without Vernal Keratoconjunctivitis.

Journal of ophthalmic & vision research

Sepehr Feizi, Mohammad Ali Javadi, Fatemeh Javadi, Mohammad Reza Jafarinasab

Affiliations

  1. Ocular Tissue Engineering Research Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
  2. Ophthalmic Research Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
  3. Department of Ophthalmology, Shahed University of Medical Sciences, Tehran, Iran.
  4. Ophthalmic Epidemiology Research Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran.

PMID: 26425311 PMCID: PMC4568606 DOI: 10.4103/2008-322X.163768

Abstract

PURPOSE: To compare the clinical outcomes of deep anterior lamellar keratoplasty (DALK) for keratoconus in patients with vernal keratoconjunctivitis (VKC) versus those without VKC.

METHODS: In this retrospective comparative study, records of 262 eyes with keratoconus (Group 1) and 28 keratoconic eyes with VKC (Group 2) that had undergone DALK were compiled. Reviewed parameters included length of follow-up, best-corrected visual acuity (BCVA), refractive error, complications and cumulative graft survival.

RESULTS: Mean duration of follow-up was 38.6 ± 20.2 and 34.4 ± 20.9 months in groups 1 and 2, respectively (P = 0.21). Mean post-operative BCVA was 0.19 ± 0.11 and 0.20 ± 0.15 logMAR, in groups 1 and 2 (P = 0.79). BCVA≥20/40 was achieved in 91.6 and 88.5% of eyes in groups 1 and 2, respectively (P = 0.48). Epithelial problems were encountered in 31.3 and 42.9% of operated eyes, respectively (P = 0.16). Vascularization of suture tracts and stitch abscesses were encountered more frequently in the eyes with VKC (P = 0.01 and <0.001, respectively). At the 33-month follow-up examination, rejection-free graft survival rates were 56.0% in group 1 and 33.3% in group 2, with mean durations of 41.0 and 32.1 months, respectively (P = 0.15). Graft survival rates were 98.1% in group 1 and 95.0% in group 2, with mean durations of 88.6 and 88.4 months, respectively (P = 0.74).

CONCLUSION: Clinical outcomes of DALK in keratoconic eyes with VKC were comparable to those in eyes with keratoconus alone. However, complications such as suture tract vascularization and stitch abscesses were more common when VKC coexisted, necessitating closer monitoring.

Keywords: Deep Anterior Lamellar Keratoplasty; Graft Survival; Keratoconus; Vernal Keratoconjunctivitis

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