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J Anim Sci Biotechnol. 2015 Aug 25;6(1):40. doi: 10.1186/s40104-015-0038-8. eCollection 2015.

Chicken egg yolk antibodies (IgY) as non-antibiotic production enhancers for use in swine production: a review.

Journal of animal science and biotechnology

Xiaoyu Li, Lili Wang, Yuhong Zhen, Shuying Li, Yongping Xu

Affiliations

  1. School of Life Science and Technology, Dalian University of Technology, Dalian, 116024 China ; Ministry of Education Center for Food Safety of Animal Origin, Dalian, 116620 China.
  2. Department of Pharmacy, Dalian Medical University, Dalian, 116044 China.
  3. Dalian SEM Bio-Engineering Technology Co. Ltd, Dalian, 116620 China.

PMID: 26309735 PMCID: PMC4549021 DOI: 10.1186/s40104-015-0038-8

Abstract

In recent years, the use of in-feed antibiotics for growth and disease prevention in livestock production has been under severe scrutiny. The use and misuse of in-feed antibiotics has led to problems with drug residues in animal products and increased bacterial resistance. Chicken egg yolk antibodies (IgY) have attracted considerable attention as an alternative to antibiotics to maintain swine health and performance. Oral administration of IgY possesses many advantages over mammalian IgG such as cost-effectiveness, convenience and high yield. This review presents an overview of the potential to use IgY immunotherapy for the prevention and treatment of swine diarrhea diseases and speculates on the future of IgY technology. Included are a review of the potential applications of IgY in the control of enteric infections of either bacterial or viral origin such as enterotoxigenic Escherichia coli, Salmonella spp., rotavirus, porcine transmissible gastroenteritis virus, and porcine epidemic diarrhea virus. Some potential obstacles to the adoption of IgY technology are also discussed.

Keywords: Diarrhea; Disease control; Egg yolk antibodies; IgY; Swine

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