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Chong JJ, Fragaszy E, Dukes O, et al. Serum Albumin Concentrations in a Multi-Ethnic Cohort of Patients with Human Immunodeficiency Virus Infection from South East London. Biores Open Access. 2015;4(1):160-3doi: 10.1089/biores.2014.0038.
Chong, J. J., Fragaszy, E., Dukes, O., Cason, J., & Kozlakidis, Z. (2015). Serum Albumin Concentrations in a Multi-Ethnic Cohort of Patients with Human Immunodeficiency Virus Infection from South East London. BioResearch open access, 4(1), 160-3. https://doi.org/10.1089/biores.2014.0038
Chong, James Jy, et al. "Serum Albumin Concentrations in a Multi-Ethnic Cohort of Patients with Human Immunodeficiency Virus Infection from South East London." BioResearch open access vol. 4,1 (2015): 160-3. doi: https://doi.org/10.1089/biores.2014.0038
Chong JJ, Fragaszy E, Dukes O, Cason J, Kozlakidis Z. Serum Albumin Concentrations in a Multi-Ethnic Cohort of Patients with Human Immunodeficiency Virus Infection from South East London. Biores Open Access. 2015 Feb 01;4(1):160-3. doi: 10.1089/biores.2014.0038. eCollection 2015. PMID: 26309792; PMCID: PMC4497629.
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Biores Open Access. 2015 Feb 01;4(1):160-3. doi: 10.1089/biores.2014.0038. eCollection 2015.

Serum Albumin Concentrations in a Multi-Ethnic Cohort of Patients with Human Immunodeficiency Virus Infection from South East London.

BioResearch open access

James Jy Chong, Ellen Fragaszy, Oliver Dukes, John Cason, Zisis Kozlakidis

Affiliations

  1. King's College London, School of Medicine , Guy's Campus, Guy's Hospital, Great Maze Pond, London, United Kingdom .
  2. University College London , Institute of Health Informatics and the Farr Institute of Health Informatics Research, London, United Kingdom .
  3. University College London , Infection and Immunity and the Farr Institute of Health Informatics Research, London, United Kingdom .

PMID: 26309792 PMCID: PMC4497629 DOI: 10.1089/biores.2014.0038

Abstract

Human albumin is the most abundant protein in sera and a valuable biomarker in monitoring a variety of diseases. In this study we investigated the relationship between serum albumin concentrations and effects of initiation of highly active antiretroviral therapy (HAART). Serum albumin concentrations amongst 70 HIV-infected patients from diverse ethnicities were analyzed, in the absence of any other confounding comorbidities, over a period of 8 years in South East London, United Kingdom. Serum albumin data was collected, on average, every 4-6 weeks during routine visits. Serum albumin was measured prior to starting HAART, and measured at the first clinic visit after commencing HAART. These were compared to a control group of untreated individuals. Based on our analyses we conclude that serum albumin concentrations increase significantly after the initiation of therapy.

Keywords: HIV; biomarkers; virology

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